SEARCH FOCUS SYNTHESIS STRUCTURES ONLINECompany ProfileFocus Synthesis LLC sells fine research chemicals and provides custom synthesis oursourcing services. Our main purpose is to accelerate drug discovery by providing unique, rationally designed building blocks. Focus product lines include: (1) Rare and Unique Substructure Classes: Many Focus products belong to substructure classes that are rare or unavailable in other chemical catalogs. The rare substructures make these products ideal for the development of non-obvious variations on current lead molecules, thereby strengthening intellectual property as well as improving diversity and property space coverage. (2) ?Rule of Three? Building Blocks: Recently, a set of rules has been developed by Congreve et al. to help identify small molecules suited for the fragment-based lead discovery They determined that small molecules that obey the "Rule of Three" are most suited to this approach: FW Cheminformatic Gap Fillers have been designed to occupy these empty spaces and so significantly enhance the diversity of libraries derived from them.Featured Structures