Emodin

• Product NameEmodin
  CAS No.518-82-1
  Purity97-99%
  Min QuantityKilograms
  Price~
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  Molecular Structure

Detailed Description

Emodin (from Rheum emodi, a Himalayan rhubarb) is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, buckthorn and Japanese knotweed (Fallopia japonica syn. Polygonum cuspidatum).[1] It can also be isomers in botanical extracts.
Emodin is being studied as a potential agent that could reduce the impact of type 2 diabetes. It is a potent selective inhibitor of the enzyme 11β-HSD1.[2] In studies in obese mice, emodin limits the effect of glucocorticoids and may therefore ameliorate diabetes and insulin resistance.[3]

Pharmacological studies have demonstrated that emodin when isolated from rhubarb exhibits anti-cancer effects on several human cancers, including human pancreatic cancer.[4][5][6] Emodin in rhubarb extracts may also have neuroprotective properties against glutamate toxicity.[7]

Aloe-emodin (1,3,8-trihydroxyanthraquinone) is a variety of emodin found in Socotrine, Barbados, and Zanzibar aloes, but not in Natal aloes.[citation needed]

Emodin is also shown to block cytomegalovirus infections as well as herpes simplex. Research is currently being performed in this area.