Home > Name List By p > Pregn-4-ene-3,20-dione,17-(acetyloxy)-6-(trifluoromethyl)-, (6a)- (9CI)

CAS No 987-18-8 , Pregn-4-ene-3,20-dione,17-(acetyloxy)-6-(trifluoromethyl)-, (6a)- (9CI)

  • Name: Pregn-4-ene-3,20-dione,17-(acetyloxy)-6-(trifluoromethyl)-, (6a)- (9CI)
  • Synonyms: Pregn-4-ene-3,20-dione,17-hydroxy-6a-(trifluoromethyl)-,acetate (7CI,8CI); 17-Hydroxy-6a-(trifluoromethyl)pregn-4-ene-3,20-dione acetate;Demigrana; Leomigran; Flumedroxone acetate; 6a-(Trifluoromethyl)-17-hydroxyprogesteroneacetate; Demigran; NSC 52412;17-Hydroxy-6a-(trifluoromethyl)progesteroneacetate;Pregn-4-ene-3,20-dione,17-(acetyloxy)-6-(trifluoromethyl)-, (6a)- (9CI); 6a-Trifluoromethyl-17a-acetoxyprogesterone; 17-Acetoxy-6a-(trifluoromethyl)progesterone; WG 537;
  • CAS Registry Number:
  • Flash Point: 241.9°C
  • Boiling Point: 491.3°Cat760mmHg
  • Density: 1.23g/cm3
  • Refractive index: 1.513
  • Flash Point: 241.9°C
  • EINECS: 213-577-0
  • Molecular Weight: 440.4957496
  • InChI: InChI=1/C24H31F3O4/c1-13(28)23(31-14(2)29)10-7-18-16-12-20(24(25,26)27)19-11-15(30)5-8-21(19,3)17(16)6-9-22(18,23)4/h11,16-18,20H,5-10,12H2,1-4H3/t16-,17+,18+,20+,21-,22+,23+/m1/s1
  • Molecular Formula: C24H31 F3 O4
  • Molecular Structure:CAS No:987-18-8 Pregn-4-ene-3,20-dione,17-(acetyloxy)-6-(trifluoromethyl)-, (6a)- (9CI)

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References of Pregn-4-ene-3,20-dione,17-(acetyloxy)-6-(trifluoromethyl)-, (6a)- (9CI)
Title: Flumedroxone Acetate
CAS Registry Number: 987-18-8
CAS Name: (6a)-17-(Acetyloxy)-6-(trifluoromethyl)pregn-4-ene-3,20-dione
Synonyms: 17-hydroxy-6a-(trifluoromethyl)pregn-4-ene-3,20-dione acetate; 17-acetoxy-6a-(trifluoromethyl)progesterone; 17-hydroxy-6a-(trifluoromethyl)progesterone acetate; 6a-(trifluoromethyl)-17-hydroxyprogesterone acetate
Manufacturers' Codes: WG-537
Trademarks: Demigran (Leo Pharm)
Molecular Formula: C24H31F3O4
Molecular Weight: 440.50
Percent Composition: C 65.44%, H 7.09%, F 12.94%, O 14.53%
Literature References: Prepn: Godtfredsen, Vangedal, Acta Chem. Scand. 15, 1786 (1961); Godtfredsen, GB 905694 (1962 to L?vens Komiske Fabrik). Solubilization study: T. Lovgren et al., Acta Pharm. Suec. 15, 233 (1978).
Properties: Solid, mp 206-207°. [a]D20 +30°. uv max (ethanol): 234 nm (e 15600).
Melting point: mp 206-207°
Optical Rotation: [a]D20 +30°
Absorption maximum: uv max (ethanol): 234 nm (e 15600)
Therap-Cat: Antimigraine.
Keywords: Antimigraine.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.