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CAS No 2668-66-8 , Pregn-4-ene-3,20-dione,11-hydroxy-6-methyl-, (6a,11b)-

  • Name: Pregn-4-ene-3,20-dione,11-hydroxy-6-methyl-, (6a,11b)-
  • Synonyms: 11b-Hydroxyl medroxyprogesterone; HMS;Pregn-4-ene-3,20-dione,11b-hydroxy-6a-methyl- (7CI,8CI); U 8471; Medrifar; Ophtocortin;Pregn-4-ene-3,20-dione,11-hydroxy-6-methyl-, (6a,11b)-; Visudrisone; 11b-Hydroxy-6a-methylpregn-4-ene-3,20-dione;Hydroxymesterone;Spectamedryn; NSC 63278; 6a-Methyl-D4-pregnene-11b-hydroxy-3,20-dione; Medrocort; Medrysone; 11b-Hydroxy-6a-methylprogesterone;
  • CAS Registry Number:
  • Flash Point: 265.7°C
  • Boiling Point: 492.3°Cat760mmHg
  • Density: 1.13g/cm3
  • Refractive index: 1.552
  • Safety Statements: WGK Germany 3 RTECS TU5250000
  • Flash Point: 265.7°C
  • EINECS: 220-208-7
  • Molecular Weight: 344.49
  • InChI: InChI=1/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15?,16+,17?,19-,20?,21-,22+/m0/s1
  • Molecular Formula: C22H32O3
  • Molecular Structure:CAS No:2668-66-8 Pregn-4-ene-3,20-dione,11-hydroxy-6-methyl-, (6a,11b)-

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2668-66-8 Medrysone

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2668-66-8 6ALPHA-METHYL-11BETA-HYDROXYPROGESTERONE

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References of Pregn-4-ene-3,20-dione,11-hydroxy-6-methyl-, (6a,11b)-
Title: Medrysone
CAS Registry Number: 2668-66-8
CAS Name: (6a,11b)-11-Hydroxy-6-methylpregn-4-ene-3,20-dione
Synonyms: 11b-hydroxy-6a-methylprogesterone; 6a-methyl-11b-hydroxyprogesterone; hydroxymesterone
Manufacturers' Codes: U-8471
Trademarks: HMS (Allergan)
Molecular Formula: C22H32O3
Molecular Weight: 344.49
Percent Composition: C 76.70%, H 9.36%, O 13.93%
Literature References: Prepn and use as an intermediate: Sebek et al., Spero, Thompson, US 2864837 and US 2968655 (1958 and 1961, both to Upjohn). In treatment of ocular inflammation: Bedrossian, Arch. Ophthalmol. 81, 184 (1969).
Properties: Crystals, mp 155-158°. [a]D +189° (in chloroform).
Melting point: mp 155-158°
Optical Rotation: [a]D +189° (in chloroform)
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.