Home > Name List By 2 > 2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5- methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid

CAS No 96314-96-4 , 2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-
methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid

  • Name: 2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-
    methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid
  • Synonyms: 2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-
    methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid; 96314-96-4;Indo 1;
  • CAS Registry Number:
  • Flash Point: 1016.3°Cat760mmHg
  • Boiling Point: 1016.3°Cat760mmHg
  • Density: 1.527g/cm3
  • Refractive index: 1.707
  • Safety Statements: S22;S24/25
  • Flash Point: 1016.3°Cat760mmHg
  • Molecular Weight: 649.60144
  • InchiKey: AMHAQOBUZCQMHN-UHFFFAOYSA-N
  • InChI: InChI=1S/C32H31N3O12/c1-18-2-6-24(34(14-28(36)37)15-29(38)39)26(10-18)
    46-8-9-47-27-13-20(5-7-25(27)35(16-30(40)41)17-31(42)43)22-11-19-3-4-21
    (32(44)45)12-23(19)33-22/h2-7,10-13,33H,8-9,14-17H2,1H3,(H,36,37)(H,38,
    39)(H,40,41)(H,42,43)(H,44,45)
  • Risk Statements: S22;S24/25
  • Molecular Formula: C32H31N3O12
  • Molecular Structure:CAS No:96314-96-4 2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-<br />methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid

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96314-96-4 I-018 INDO-1, PENTAPOTASSIUM SALT

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96314-96-4 for fluorescence

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96314-96-4 INDO 1 FOR FLUORESCENCE

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96314-96-4 INDO-1

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References of 2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-
methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid
Title: Indo-1
CAS Registry Number: 96314-96-4
CAS Name: 2-[4-[Bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid
Synonyms: 1-[2-amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2￠-amino-5-methylphenoxy)ethane-N,N,N￠,N￠-tetraacetic acid
Molecular Formula: C32H31N3O12
Molecular Weight: 649.60
Percent Composition: C 59.17%, H 4.81%, N 6.47%, O 29.56%
Literature References: Fluorescent calcium imaging agent; structurally related to BAPTA, q.v. Ca2+ binding causes a spectral shift to shorter wavelengths; ratio of the fluorescence at each wavelength is related to changes in Ca2+ binding and independent of dye concentration. Synthesis and characterization: G. Grynkiewicz et al., J. Biol. Chem. 260, 3440 (1985). Acid-base and calcium binding properties: F. Bancel et al., J. Photochem. Photobiol. A 53, 397 (1990); spectral properties: H. Szmacinski et al., Biophys. J. 70, 547 (1996). Practical aspects of use in intracellular measurements: K. R. Sipido, G. Callewaert, Cardiovasc. Res. 29, 717 (1995). Detection of other metal cations: G. A. Peeters et al., Am. J. Physiol. 256, C351 (1989); J. R. Jefferson et al., Anal. Biochem. 187, 328 (1990). Review of use in plant cells: D. S. Bush, R. L. Jones, Plant Physiol. 93, 841-845 (1990).
Properties: uv max absorption (100mM KCl): 349 nm free dye; 331 nm Ca2+ complex; emission maxima: 485 nm free dye; 410 nm Ca2+ complex. pKa1: 6.2; pKa2: 4.35.
pKa: pKa1: 6.2; pKa2: 4.35
Absorption maximum: uv max absorption (100mM KCl): 349 nm free dye; 331 nm Ca2+ complex
Use: Fluorescent probe primarily for measuring calcium in biological systems.