CAS No 939981-39-2 , [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,
5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]
methanone

Name: [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,
5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]
methanone
Synonyms: UNII-Q8MI0X869M; RG7112|939981-39-2|RG 7112; SureCN12704861; RG 7112; CS-0330; RG7112;[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,
5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]
methanone; HY-10959;
CAS Registry Number:939981-39-2
Density: 1.23
Molecular Weight: 727.78312
InchiKey: QBGKPEROWUKSBK-QPPIDDCLSA-N
InChI: InChI=1S/C38H48Cl2N4O4S/c1-8-48-33-26-29(36(2,
3)4)14-19-32(33)34-41-37(5,27-10-15-30(39)16-11-27)38(6,
28-12-17-31(40)18-13-28)44(34)35(45)43-23-21-42(22-24-43)20-9-25-49(7,
46)47/h10-19,26H,8-9,20-25H2,1-7H3/t37-,38+/m0/s1
Molecular Formula: C₃₈H₄₈Cl₂N₄O₄S
Molecular Structure:

RG7112 RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2. IC50 Value: Target: MDM2/p53 Restoration of p53 activity by inhibiting the p53-MDM2 interaction may represent a novel approach to can...
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CAS No 939981-39-2 , [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone