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CAS No 92-31-9 , (7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium

  • Name: (7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium
  • Synonyms: Menodin; Tolazul;Toluidine Blue O;chloride; Gabilin; TOLONIUM CHLORIDE; Toluidine Blue; Tolonium; Basic Blue 17; Blutene chloride; Blutene;(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium;
  • CAS Registry Number:
  • Water Solubility: 3.82 G/100 ML
  • Safety Statements: 22-24/25
  • HS Code: 32041300
  • EINECS: 202-146-2
  • Molecular Weight: 305.82564
  • InchiKey: GEDVVYWLPUPJJZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H15N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12
    (14)17-13;/h4-8,16H,1-3H3;1H
  • Risk Statements: S24/25
  • Molecular Formula: C15H16ClN3S
  • Molecular Structure:CAS No:92-31-9 (7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium
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92-31-9 TOLUIDINE BLUE O, CERTIFICATED

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany ,Germany
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92-31-9 TOLUIDINE BLUE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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92-31-9 Tolonium chloride

  • United States Tyger Scientific Inc. [Manufacturer]
  • Tel: 888-329-8990/ 609-434-0144
  • Fax: 609-434-0143
  • Address: Tyger Scientific Inc.
    324 Stokes Avenue
    Ewing, New Jersey 08638 ,United States
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92-31-9 TOLUIDINE BLUE (C.I. 52040)

  • Germany AppliChem GmbH [Manufacturer]
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: AppliChem GmbH
    Ottoweg 4
    64291 Darmstadt
    Germany ,Germany
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92-31-9 A20785 3-AMINO-7-DIMETHYLAMINO-2-METHYLPHENAZATHIONIUM CH

  • United States Pfaltz & Bauer [Manufacturer]
  • Tel: (203) 574-0075
  • Fax: (203) 574-3181
  • Address: 172 E. Aurora St.
    Waterbury, CT 06708 ,United States
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92-31-9 T-3922 TOLUIDINE BLUE

  • Switzerland Biosynth AG [Manufacturer]
  • Tel: +41 71 858 20 20/ 630.305.8400 (USA)
  • Fax: +41 71 858 20 30
  • Address: BIOSYNTH AG
    Rietlistrasse 4
    9422 Staad / Switzerland
    Phone: +41 (0)71 858 20 20
    Fax: +41 (0)71 858 20 30 ,Switzerland
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92-31-9 Tolonium chloride

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92-31-9 TOLUIDINE BLUE O

  • United States AMRESCO Inc. [Manufacturer]
  • Tel: 440-349-1313
  • Fax: 440-349-1182
  • Address: AMRESCO Inc.
    30175 Solon Industrial Parkway
    Solon, OH 44139 ,United States
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92-31-9 Tolonium chloride

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92-31-9 Tolonium chloride

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References of (7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium
Title: Tolonium Chloride
CAS Registry Number: 92-31-9
CAS Name: 3-Amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride
Synonyms: 3-amino-7-dimethylamino-2-methylphenazathionium chloride; toluidine blue O; dimethyltoluthionine chloride; C.I. Basic Blue 17; C.I. 52040
Trademarks: Blutene (Abbott); Klot (Warren-Teed); Tolazul
Molecular Formula: C15H16ClN3S
Molecular Weight: 305.83
Percent Composition: C 58.91%, H 5.27%, Cl 11.59%, N 13.74%, S 10.48%
Literature References: Prepd from dimethyl-p-phenylenediamine, sodium thiosulfate, and o-toluidine: D?ndliker, Bernthsen, US 416055 (1888 to BASF). Prepn of hemostatic compositions contg tolonium chloride: D. A. Hoff, US 2809913 (1957 to Warren-Teed). Prepn of clear, colorless, stable, isotonic solns of purified leucotoluidine blue O by reducing toluidine blue O with sodium hydrosulfite at pH 2.5-3.5: B. March, E. E. Moore, US 2571593 (1951 to Abbott). Clinical studies in bleeding disorders: J. Allen et al., Surg. Gynecol. Obstet. 89, 692 (1949). Clinical use for parathyroid identification during thyroidectomy: R. M. Yeager, E. T. Krementz, Ann. Surg. 169, 829 (1969). Acute and chronic toxicity study: T. J. Haley, F. Stolarsky, Stanford Med. Bull. 9, 96 (1951). Review of therapeutic and diagnostic use: A. Mashberg, J. Am. Dent. Assoc. 106, 319-323 (1983). See also Colour Index vol. 4 (3rd ed., 1971) p 4471; H. J. Conn's Biological Stains, R. D. Lillie, Ed. (Williams & Wilkins, Baltimore, 9th ed., 1977) p 428.
Properties: Dark green powder. Sol in water (3.82 g/100 ml), giving a blue to violet soln; sol in alc (0.57 g/100 ml), giving a blue soln. Absorption max (water): 640.4 nm. LD50 in mice, rats, rabbits (mg/kg): 27.56, 28.93, 13.44 i.v. (Haley, Storlarsky).
Absorption maximum: Absorption max (water): 640.4 nm
Toxicity data: LD50 in mice, rats, rabbits (mg/kg): 27.56, 28.93, 13.44 i.v. (Haley, Storlarsky)
Use: Direct dyeing, printing of wool, silk. Biological stain.
Therap-Cat: Hemostatic. Diagnostic aid (oral carcinoma).
Keywords: Diagnostic Aid; Hemostatic.