Home > Name List By 2 > 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2- phenoxyethyl)-1,2,4-triazol-3-one

CAS No 9046-56-4 , 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-
phenoxyethyl)-1,2,4-triazol-3-one

  • Name: 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-
    phenoxyethyl)-1,2,4-triazol-3-one
  • Synonyms: Nefazodone Hcl; Nefazodona [Spanish]; 83366-66-9; CHEBI:7494; Nefazodonum;2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-
    phenoxyethyl)-1,2,4-triazol-3-one;Nefazodonum [Latin]; Nefazodona; Nefazodone (INN);
  • CAS Registry Number:
  • Safety Statements: An experimental teratogen. Experimental reproductive effects.
  • EINECS: 232-933-6
  • Molecular Weight: 470.00688
  • InchiKey: VRBKIVRKKCLPHA-UHFFFAOYSA-N
  • InChI: InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-
    23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,
    12-19H2,1H3
  • Molecular Formula: C25H32ClN5O2
  • Molecular Structure:CAS No:9046-56-4 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-<br />phenoxyethyl)-1,2,4-triazol-3-one

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References of 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-
phenoxyethyl)-1,2,4-triazol-3-one
Title: Ancrod
CAS Registry Number: 9046-56-4
CAS Name: Agkistrodon serine proteinase
Synonyms: Agkistrodon rhodostoma venom proteinase
Manufacturers' Codes: A-38414
Trademarks: Arvin (Knoll); Arwin (Knoll); Viprinex (Knoll)
Literature References: Defibrinating enzyme isolated from the venom of the Malayan pit-viper, Agkistrodon rhodostoma Boie (Calloselasma rhodostoma Boie). Glycosylated serine protease composed of 234 amino acid residues; mol wt ~35,400. Cleaves fibrinogen to form soluble, non-cross-linked fibrin and enhances the local release of tissue plasminogen activator, q.v. Isoln: NL 6502120; H. A. Reid et al., US 3657416 (1965, 1972 to Nat. Res. Dev. Corp.); K. E. Chan et al., Br. J. Haematol. 11, 646 (1965). Initial purification: M. P. Esnouf, G. W. Tunnah, ibid. 13, 581 (1967). Improved purification, chemical composition: C. Nolan et al., Methods Enzymol. 45, 205 (1976). Mechanism of action studies: W. R. Bell et al., J. Lab. Clin. Med. 91, 592 (1978); C. R. M. Prentice et al., Br. J. Haematol. 83, 276 (1993). Review of clinical pharmacology and efficacy: K. A. Illig, K. Ouriel, Semin. Vasc. Surg. 9, 303-314 (1996). Review of use in anticoagulant therapy: R. L. Soutar, J. S. Ginsberg, Crit. Rev. Oncol. Hematol. 15, 23-33 (1993); in acute ischemic stroke: R. P. Atkinson, Drugs 54, Suppl. 3, 100-108 (1997).
Properties: Colorless substance when pure, having a light powdery texture when in the freeze-dried state. Soluble in physiological saline. Absorbable on weakly basic anion exchange materials.
Therap-Cat: Anticoagulant.
Keywords: Anticoagulant.