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CAS No 9007-92-5 , Glucagon

  • Name: Glucagon
  • Synonyms: 9007-92-5;Glucagon; HG-Factor; Glukagon; Glucagone;Glucagonum;
  • CAS Registry Number:
  • Melting Point: -15 deg C
  • Boiling Point: 230 deg C at 760 mm Hg
  • Safety Statements: Human systemic effects by intramuscular route: leukopenia (reduced white blood cell count). An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
  • EINECS: 232-708-2
  • Molecular Weight: 3482.7473
  • InchiKey: MASNOZXLGMXCHN-ZLPAWPGGSA-N
  • InChI: InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132
    (225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-
    137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-
    114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-
    79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-
    124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-
    23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)
    216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)
    180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100
    (57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)
    111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-
    27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112
    (156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-
    84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,
    30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,
    208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,
    221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,
    228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,
    225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,
    229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,
    236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,
    163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,
    100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,
    122-,123-/m0/s1
  • Molecular Formula: C153H225N43O49S
  • Molecular Structure:CAS No:9007-92-5 Glucagon

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9007-92-5 GLUCAGON HCL(HUMAN)

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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9007-92-5 Glucagon

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  • Address: 519 Zi Yue Road, Shanghai, China 200241, ShangHai,ShangHaiChina
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9007-92-5 Glucagon

  • United States Aceto Corporation [Importer/Exporter]
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  • Address: One Hallow Lane, Lake Success, New York 11042-1215, null,nullUnited States
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9007-92-5 Glucagon

  • China Sinopep Pharmaceutical Inc. [Manufacturers]
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References of Glucagon
Title: Glucagon
CAS Registry Number: 9007-92-5
Synonyms: Glukagon; hyperglycemic-glycogenolytic factor; HG-factor; HGF
Literature References: Polypeptide hormone produced in the alpha cells of the islets of Langerhans in the pancreas; stimulates hepatic glucose output. Identification as hyperglycemic factor in pancreatic extracts: J. R. Murlin et al., J. Biol. Chem. 56, 253 (1923); C. P. Kimball, J. R. Murlin, ibid. 58, 337 (1923). Purification and properties: M. Bürger, W. Brandt, Z. Ges. Exp. Med. 96, 375 (1935); A. Staub et al., Science 117, 628 (1953); eidem, J. Biol. Chem. 214, 619 (1955). Amino acid sequence of porcine: W. W. Bromer et al., J. Am. Chem. Soc. 79, 2807 (1957); of bovine: idem et al., J. Biol. Chem. 246, 2822 (1971); of human: J. Thomsen et al., FEBS Lett. 21, 315 (1972). Review: O. K. Behrens, W. W. Bromer, Vitam. Horm. 16, 263-301 (1958). Books: P. J. Lefèbvre, R. H. Unger, Glucagon (Pergamon Press, New York, 1972) 535 pp; Glucagon Pts. I and II, P. Lefèbvre, Ed. (Springer, New York, 1983) 700 pp. Review of cardiovascular effects and use as antidote to beta-blocker overdose: C. M. White, J. Clin. Pharmacol. 39, 442-447 (1999); of role in glucose homeostasis: G. Jiang, B. B. Zhang, Am. J. Physiol. Endocrinol. Metab. 284, E671-E678 (2003). Review of use to decrease gastrointestinal motility during endoscopy: T. Hashimoto et al., Aliment. Pharmacol. Ther. 16, 111 (2002).
Properties: Rhombic dodecahedra. Stable. Practically insol in water. Sol in acidic, basic media, i.e. below pH 3 and above pH 9.5.
Therap-Cat: Antihypoglycemic. Diagnostic aid (adjunct for endoscopy).
Keywords: Antihypoglycemic.