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CAS No 9002-68-0 , Follicle stimulating hormone

  • Name: Follicle stimulating hormone
  • Synonyms: Human Menopausal Gonadotrophin;Follicle stimulating hormone; HMG;
  • CAS Registry Number:
  • Melting Point: 127-131 deg C
  • Water Solubility: H2O: 50 mg/mL, soluble
  • Safety Statements: Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and fumes.
  • Hazard Symbols: B
  • EINECS: 232-662-3
  • Molecular Weight: 36,000
  • InChI: InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
  • Molecular Formula: Unspecified
  • Molecular Structure:CAS No:9002-68-0 Follicle stimulating hormone
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9002-68-0 FOLLICLE-STIMULATING HORMONE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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9002-68-0 Menotropins

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9002-68-0 Follitropin

  • Follitropin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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9002-68-0 Follicle Stimulating Hormone

  • Germany AppliChem mbH null
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: Ottoweg 4 D-64291 Darmstadt null,nullGermany
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9002-68-0 Menotropins

  • Menotropins
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
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9002-68-0 Follicle Stimulating Hormone, from Porcine Pituitary

  • Follicle Stimulating Hormone, from Porcine Pituitary
  • United States MP Biomedicals LLC [Manufacturer]
  • Tel: 877 672 2436
  • Fax: 949 859 5010
  • Address: 15 Morgan Irvine CA92618 USA ,nullUnited States
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9002-68-0 FOLLICLE-STIMULATING HORMONE

  • Germany AppliChem GmbH [Manufacturer]
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: AppliChem GmbH
    Ottoweg 4
    64291 Darmstadt
    Germany null,nullGermany
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9002-68-0 Menotropins

  • United States XENOS BIORESCOURCES. INC [Importer/Exporter]
  • Tel: 636-256-8801
  • Fax: 636-256-8899
  • Address: 16229 Westwood Business Park Saint Louis, Missouri 63021 Saint Louis,MissouriUnited States
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9002-68-0 Follic stimulating Hormon

  • Follic stimulating Hormon
  • China interchem [Manufacturer]
  • Tel: +86-23-67030787
  • Fax: +86-23-67030809
  • Address: 17F.,Venus science incubation center,No.60 xingguang road,New north zone,Chongqing,China 401121 ChongiqngCHINA Chongiqng,nullChina
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9002-68-0 Menotropins

  • Germany Kraeber & Co GmbH [Manufacturer]
  • Tel: +49-4101-3053-0
  • Fax: +49-4101-3053-90
  • Address: null Ellerbek,EllerbekGermany
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References of Follicle stimulating hormone
Title: Follicle-Stimulating Hormone
CAS Registry Number: 9002-68-0
Synonyms: FSH; follitropin
Literature References: Gonadotropic hormone secreted by the anterior pituitary under the regulation of gonadotopin-releasing hormone and inhibin, q.q.v. In the female, FSH stimulates estrogen production by the granulosa cells of the ovary and induces maturation of the Graafian follicle. In the male, stimulates the Sertoli cells of the testes and promotes spermatogenesis. Glycoprotein with mol wt ~34 kDa; multiple isoforms exist. Structure is a heterodimer of noncovalently linked a and b subunits; analogous with LH, TSH and chorionic gonadotropin, q.q.v. Isoln from pituitary: H. L. Fevold et al., Endocrinology 26, 999 (1940); C. H. Li et al., Science 109, 445 (1949). Prepn of human FSH from pituitaries and from postmenopausal urine: P. Roos, Acta Endocrinol. 59, Suppl. 131, 1-93 (1968). Amino acid sequence of human FSH a-subunit: P. Rathnam, B. B. Saxena, J. Biol. Chem. 250, 6735 (1975); of human b-subunit: B. B. Saxena, P. Rathnam, ibid. 251, 993 (1976). Production in Chinese hamster ovary cells by recombinant DNA technology: J. L. Keene et al., J. Biol. Chem. 264, 4769 (1989). Characterization of isoforms: P. G. Stanton et al., Mol. Cell. Endocrinol. 125, 133 (1996). Review of structure, biosynthesis and receptor binding: J. G. Pierce, T. F. Parsons, Annu. Rev. Biochem. 50, 465-495 (1981). Review of role in spermatogenesis: R. I. McLachlan et al., J. Endocrinol. 148, 1-9 (1996); in ovarian function and clinical use: B. C. Fauser, A. M. Van Heusden, Endocr. Rev. 18, 71-106 (1997).
Properties: Solid. Isoelectric point 4.5. Soluble in water, physiological saline soln, 50% alc. uv max: 277 nm (pH 7.0 phosphate buffer); 291 nm (0.1N NaOH-8M urea).
Absorption maximum: uv max: 277 nm (pH 7.0 phosphate buffer); 291 nm (0.1N NaOH-8M urea)
 
Derivative Type: Follitropin Alfa
Trademarks: Gonal-F (Serono)
Literature References: Recombinant human FSH, glycoform a. Clinical pharmacokinetics: J.-Y. le Cotonnec et al., Fertil. Steril. 61, 669, 679 (1994). Clinical trial: T. Strowitzki et al., Hum. Reprod. 10, 3097 (1995).
 
Derivative Type: Follitropin Beta
Manufacturers' Codes: Org-32489
Trademarks: Follistim (Organon); Puregon (Organon)
Literature References: Recombinant human FSH, glycoform b. Clinical pharmacokinetics: B. Mannaerts et al., Fertil. Steril. 59, 108 (1993). Clinical trial: B. Hedon et al., Hum. Reprod. 10, 3102 (1995).
 
Derivative Type: Menotropins
Synonyms: Menotrophin; human menopausal gonadotropins
Trademarks: Humegon (Organon); Menogon (Ferring); Pergonal (Serono); Repronex (Ferring)
Literature References: Extract of human postmenopausal urine containing both FSH and LH.
 
Derivative Type: Urofollitropin
CAS Registry Number: 97048-13-0
Synonyms: Urofollitrophin
Trademarks: Fertinorm (Serono); Metrodin (Serono); Orgafol (Organon)
Literature References: Purified extract of human postmenopausal urine containing FSH.
 
Therap-Cat: Gonad-stimulating principle.
Therap-Cat-Vet: Gonad-stimulating principle.
Keywords: Gonad-Stimulating Principle.