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CAS No 89750-14-1 , Glucagon-like peptide I

  • Name: Glucagon-like peptide I
  • Synonyms: Glucagon-related peptide 1;Glucagon-relatedpeptide I; GLP 1;Glucagon-like peptide I; Glucagon-like peptide 1;
  • CAS Registry Number:
  • Molecular Weight: 0
  • InChI: InChI=1S/C10H11N3O/c1-12(2)10(14)8-7-11-13-6-4-3-5-9(8)13/h3-7H,1-2H3
  • Molecular Formula: C10H11N3O
  • Molecular Structure:CAS No:89750-14-1 Glucagon-like peptide I
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89750-14-1 10-101-46 GLUCAGON-LIKE PEPTIDE 1(7-37) GLP-1

  • United States Creative Peptides [Manufacturer]
  • Tel: 866-588-6325
  • Fax: 631-614-7828
  • Address: 45-16 Ramsey Road
    Shirley, NY 11967 null,nullUnited States
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89750-14-1 GLUCAGON-LIKE PEPTIDE 1

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Glucagon-like peptide I
Title: Glucagon-Like Peptides
Literature References: Bioactive peptides (GLP-1 and GLP-2) encoded within the preproglucagon gene; formed by tissue-specific, post-translational processing of proglucagon by intestinal L-cells. GLP-1 is a potent glucose-dependent stimulator of insulin secretion (incretin) and is released into the circulation in response to a meal. GLP-1 is also found in the brain and may have a role in regulating food and water intake. GLP-2 has growth-promoting effects on intestinal epithelium. Identification in hamster preproglucagon: G. I. Bell et al., Nature 302, 716 (1983); in human: idem et al., ibid. 304, 368 (1983). Reviews: D. J. Drucker, Diabetes 47, 159-169 (1998); T. J. Kieffer, J. F. Habener, Endocr. Rev. 20, 876-913 (1999).
 
Derivative Type: GLP-1
CAS Registry Number: 89750-14-1
CAS Name: Glucagon-like peptide I
Synonyms: glucagon-related peptide I
Literature References: Originally identified as a 37 amino acid peptide, GLP-1 (1-37), that is truncated to the bioactive forms, GLP-1 (7-37) and GLP-1 (7-36) amide. Stimulates insulin secretion, suppresses glucagon secretion and delays gastric emptying. Identification of active structure: S. Mojsov et al., J. Clin. Invest. 79, 616 (1987). Role in appetite control: I. Gunn et al., J. Endocrinol. 155, 197-200 (1997). Review of physiology and therapeutic potential in diabetes: M. A. Nauck, Acta Diabetol. 35, 117-129 (1998); J. J. Holst, Curr. Med. Chem. 6, 1005-1017 (1999).
 
Derivative Type: GLP-2
CAS Registry Number: 89750-15-2
CAS Name: Glucagon-like peptide II
Synonyms: glucagon-related peptide II
Literature References: Sequence contains 33 amino acid residues. Identification of bioactivity: D. J. Drucker et al., Proc. Natl. Acad. Sci. USA 93, 7911 (1996). Review of biological properties and therapeutic potential: idem et al., J. Parenter. Enteral Nutr. 23, Suppl., S98-S100 (1999).