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CAS No 88430-50-6 , Beraprost

  • Name: Beraprost
  • Synonyms: 2,3,3a,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta[b]benzofuran-5-butanoic acid;Beraprost;
  • CAS Registry Number:
  • Flash Point: 572.1 °C at 760 mmHg
  • Boiling Point: 572.1 °C at 760 mmHg
  • Density: 1.254 g/cm3
  • Refractive index: 1.624
  • Flash Point: 572.1 °C at 760 mmHg
  • Molecular Weight: 398.49
  • InChI: InChI=1/C24H30O5/c1-3-4-7-15(2)19(25)13-12-17-20(26)14-21-23(17)18-10-5-8-16(24(18)29-21)9-6-11-22(27)28/h5,8,10,12-13,15,17,19-21,23,25-26H,6-7,9,11,14H2,1-2H3,(H,27,28)/b13-12+/t15?,17-,19+,20+,21-,23-/m0/s1
  • Molecular Formula: C24H30O5
  • Molecular Structure:CAS No:88430-50-6 Beraprost

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References of Beraprost
Title: Beraprost
CAS Registry Number: 88430-50-6
CAS Name: 2,3,3a,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta(b)benzofuran-5-butanoic acid
Synonyms: dl-16-methyl-18,19-tetradehydro-5,6,7-trinor-4,8-inter-m-phenyleneprostaglandin I2; dl-4-[(1R,2R,3aS,8bS)-1,2,3a,8b-tetrahydro-2-hydroxy-[(3S,4RS)-3-hydroxy-4-methyl-oct-6-yne-(E)-1-enyl]-5-cyclopenta(b)benzofuranyl]butanoic acid; befaprost
Manufacturers' Codes: ML-1229
Molecular Formula: C24H30O5
Molecular Weight: 398.49
Percent Composition: C 72.34%, H 7.59%, O 20.08%
Literature References: Platelet aggregation inhibitor; stable analog of prostacyclin, q.v. Prepn: K. Ohno et al., EP 84856; eidem, US 4474802 (1983, 1984 both to Toray); eidem, Adv. Prostaglandin Thromboxane Leukotriene Res. 15, 279 (1985). PGI2 receptor binding: N. Kajikawa et al., Arzneim.-Forsch. 39, 495 (1989). Series of articles on pharmacology: ibid. 856-876. Clinical pharmacokinetics: J.-L. Demolis et al., J. Cardiovasc. Pharmacol. 22, 711 (1993). Clinical trial in intermittent claudication: M. Lievre et al., ibid. 27, 788 (1996); in diabetic angiopathy: Y. Okuda et al., Prostaglandins 52, 375 (1996).
 
Derivative Type: Sodium salt
CAS Registry Number: 88475-69-8
Manufacturers' Codes: ML-1129; TRK-100
Trademarks: Dorner (Toray); Procylin (Kaken)
Molecular Formula: C24H29NaO5
Molecular Weight: 420.47
Percent Composition: C 68.56%, H 6.95%, Na 5.47%, O 19.03%
 
Therap-Cat: Antithrombotic; vasodilator (peripheral).
Keywords: Prostaglandin/Prostaglandin Analog; Vasodilator (Peripheral); Antithrombotic.