Home > Name List By 2 > 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S, 3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2- oxoethylidene]a...

CAS No 87638-04-8 , 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,
3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-
oxoethylidene]amino]oxyacetic acid

  • Name: 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,
    3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-
    oxoethylidene]amino]oxyacetic acid
  • Synonyms: Ro 17-2301/006; AC1O712K; Carumonamum;CRMN;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,
    3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-
    oxoethylidene]amino]oxyacetic acid; Carumonam (INN); CHEBI:55486; AMA 1080; 87638-04-8; AKOS015961995;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 2.13g/cm3
  • Refractive index: 1.82
  • Flash Point: °C
  • Molecular Weight: 466.40376
  • InchiKey: UIMOJFJSJSIGLV-JNHMLNOCSA-N
  • InChI: InChI=1S/C12H14N6O10S2/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5
    (1-27-12(14)23)18(10(8)22)30(24,25)26/h3,5,8H,1-2H2,(H2,13,15)(H2,14,
    23)(H,16,21)(H,19,20)(H,24,25,26)/b17-7-/t5-,8+/m1/s1
  • Molecular Formula: C12H14N6O10S2
  • Molecular Structure:CAS No:87638-04-8 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,<br />3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-<br />oxoethylidene]amino]oxyacetic acid

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87638-04-8 Acetic acid,2-[[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-

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87638-04-8 Carumonam

  • Carumonam, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
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  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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87638-04-8 Carumonam

  • Carumonam, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
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  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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87638-04-8 Carumonam

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87638-04-8 Carumonam

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87638-04-8 CARUMONAM

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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References of 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,
3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-
oxoethylidene]amino]oxyacetic acid
Title: Carumonam
CAS Registry Number: 87638-04-8
CAS Name: [[(Z)-[2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
Synonyms: (Z)-[[[(2-amino-4-thiazolyl)[[(2S,3S)-2-(hydroxymethyl)-4-oxo-1-sulfo-3-azetidinyl]carbamoyl]methylene]amino]oxy]acetic acid carbamate (ester); (3S,4S)-cis-3-[2-(2-amino-4-thiazolyl)-2-(Z)-carboxymethoxyiminoacetamido]-4-carbamoyloxymethyl-2-azetidinone-1-sulfonic acid
Molecular Formula: C12H14N6O10S2
Molecular Weight: 466.40
Percent Composition: C 30.90%, H 3.03%, N 18.02%, O 34.30%, S 13.75%
Literature References: Synthetic monocyclic b-lactam (monobactam) antibiotic. Prepn: S. Kishimoto et al., EP 93376; T. Matsuo et al., US 4572801 (1983, 1986 both to Takeda); M. Sendai et al., J. Antibiot. 38, 346 (1985). Alternate synthesis: P. S. Manchard et al., J. Org. Chem. 53, 5507 (1988). Comparative in vitro antimicrobial activity: R. J. Fass, V. L. Helsel, Antimicrob. Agents Chemother. 28, 834 (1985); B. R. Smith et al., ibid. 29, 346 (1986); I. M. Hoepelman et al., Chemotherapy (Basel) 33, 103 (1987). b-Lactamase stability: R. L. Then, ibid. 30, 398 (1984). Pharmacokinetics in humans: E. Weidekamm et al., Antimicrob. Agents Chemother. 26, 898 (1984); C. A. M. McNulty et al., ibid. 28, 425 (1985).
Properties: Colorless powder. [a]D26 -45° (c = 1 in DMSO).
Optical Rotation: [a]D26 -45° (c = 1 in DMSO)
 
Derivative Type: Disodium salt
CAS Registry Number: 86832-68-0
Manufacturers' Codes: AMA-1080; Ro-17-2301
Trademarks: Amasulin (Takeda); Mobactam (Takeda)
Molecular Formula: C12H12N6Na2O10S2
Molecular Weight: 510.37
Percent Composition: C 28.24%, H 2.37%, N 16.47%, Na 9.01%, O 31.35%, S 12.57%
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Monobactams.