Home > Name List By 3 > 3-O-methyl 5-O-(2-oxopropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate China

CAS No 86780-90-7 , 3-O-methyl 5-O-(2-oxopropyl)
2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Search by region : China

  • Name: 3-O-methyl 5-O-(2-oxopropyl)
    2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Synonyms: Sapresta; Aranidipine [INN]; Mpc-1304; DSSTox_CID_28575; CCRIS 6724; MPC 1304; NCGC00182054-02;3-O-methyl 5-O-(2-oxopropyl)
    2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; DSSTox_RID_82847; 86780-90-7;
  • CAS Registry Number:
  • Density: 1.284 g/cm3
  • Refractive index: 1.555
  • Molecular Weight: 388.3713
  • InchiKey: NCUCGYYHUFIYNU-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H20N2O7/c1-10(22)9-28-19(24)16-12(3)20-11(2)15(18(23)27-4)17
    (16)13-7-5-6-8-14(13)21(25)26/h5-8,17,20H,9H2,1-4H3
  • Molecular Formula: C19H20N2O7
  • Molecular Structure:CAS No:86780-90-7 3-O-methyl 5-O-(2-oxopropyl)<br />2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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86780-90-7 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 3-methyl 5-(2-oxopropyl)ester

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86780-90-7 Aranidipine

  • Aranidipine
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
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86780-90-7 Aranidipine

  • Aranidipine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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86780-90-7 Aranidipine

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
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86780-90-7 Aranidipine

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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86780-90-7 Aranidipine

  • Aranidipine, 99%
  • China henglidahuagong co,.Ltd [Manufacturer]
  • Tel: 13996793719
  • Fax: 86+(0535?2260023
  • Address: NO 238,CANAN ROAD NORTH OF WENCANG,LAIZHOU CITY,SHANGDONG,CHINA LAIZHOU CITYCHINA LAIZHOU CITY,nullChina
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86780-90-7 Aranidipine

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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86780-90-7 Aranidipine

  • China Haihang Industry Co., Ltd. null
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, null,nullChina
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86780-90-7 Aranidipine

  • China Betapharma(Shanghai)Co., Ltd. null
  • Tel: +86-(21)-33538380
  • Fax: +86-(21)-32082820
  • Address: No.17#-6D. 830 Lane, Maotai Road, Shanghai 200336, null,nullChina
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86780-90-7 Aranidipine

  • Aranidipine
  • China Hangzhou Verychem Science And Technology Co., Ltd. [Manufacturer]
  • Tel: +86-571-8816 2785/ +86-571-8816 2786
  • Fax: +86-571-8816 2787
  • Address: Hangzhou Verychem Science And Technology Co., Ltd.
    1108A,316 Jiaogong Road,
    Hangzhou City,
    Zhejiang Province, China
    Post Code: 310012 null,nullChina
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References of 3-O-methyl 5-O-(2-oxopropyl)
2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Title: Aranidipine
CAS Registry Number: 86780-90-7
CAS Name: 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-oxopropyl ester
Synonyms: (±)-methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate; (±)-acetonyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate
Manufacturers' Codes: MPC-1304
Trademarks: Sapresta (Taiho)
Molecular Formula: C19H20N2O7
Molecular Weight: 388.37
Percent Composition: C 58.76%, H 5.19%, N 7.21%, O 28.84%
Literature References: Calcium channel blocker. Prepn: S. Ohno et al., FR 2514761; eidem, US 4446325 (1983, 1984 both to Maruko Seiyaku); idem et al., Chem. Pharm. Bull. 34, 1589 (1986). Pharmacology and receptor binding studies: K. Miyoshi et al., Eur. J. Pharmacol. 238, 139 (1993). Determn by GC-MS in plasma and urine: Y. Umeno et al., J. Chromatogr. 434, 123 (1988); by HPLC in plasma: Y. Iida et al., ibid. 571, 277 (1991). Cardiovascular profile: A. Kanda et al., J. Cardiovasc. Pharmacol. 22, 167 (1993). Clinical pharmacology: S. Suzuki et al., Arzneim.-Forsch. 43, 1152 (1993). Toxicity studies: S. Nakano et al., Yakuri to Chiryo 21, S931 (1993), C.A. 119, 131216 (1993).
Properties: Yellow prisms from ethyl acetate/hexane, mp 155°. LD50 in male, female mice, rats (mg/kg): 143, 193, 1982, 1459 orally; LD50 in male, female mice (mg/kg): 7.3, 9.1 i.p. (Nakano).
Melting point: mp 155°
Toxicity data: LD50 in male, female mice, rats (mg/kg): 143, 193, 1982, 1459 orally; LD50 in male, female mice (mg/kg): 7.3, 9.1 i.p. (Nakano)
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Dihydropyridine Derivatives; Calcium Channel Blocker; Dihydropyridine Derivatives.