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CAS No 86-21-5 , N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine

  • Name: N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
  • Synonyms: Feniramina [INN-Spanish]; Pyriton; Tripoton; Prophenpyridamine; Feniramine;N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine; Trimeton; Propheniramine;Avil; Metron;
  • CAS Registry Number:
  • Density: 1.018 g/cm3
  • Refractive index: 1.556
  • Safety Statements: Poison by intravenous route. Human systemic effects by ingestion: central nervous system effects. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 201-656-2
  • Molecular Weight: 240.3434
  • InchiKey: IJHNSHDBIRRJRN-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H20N2/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16/
    h3-10,12,15H,11,13H2,1-2H3
  • Molecular Formula: C16H20N2
  • Molecular Structure:CAS No:86-21-5 N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine

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References of N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
Title: Pheniramine
CAS Registry Number: 86-21-5
CAS Name: N,N-Dimethyl-g-phenyl-2-pyridinepropanamine
Synonyms: 2-[a-(2-dimethylaminoethyl)benzyl]pyridine; 1-phenyl-1-(2-pyridyl)-3-dimethylaminopropane; 3-phenyl-3-(2-pyridyl)-N,N-dimethylpropylamine; prophenpyridamine; propheniramine
Molecular Formula: C16H20N2
Molecular Weight: 240.34
Percent Composition: C 79.96%, H 8.39%, N 11.66%
Literature References: Synthesis: Sperber et al., US 2567245 and US 2676964 (1951, 1954, both to Schering).
Properties: Oily liq. Slightly yellow color. Characteristic amine-like odor. d 1.0081; bp13 181°; bp2 142°; bp0.5 135°; nD25 1.5519 to 1.5521. Insol in water. Sol in dil acids, alcohol, benzene, chloroform, ether.
Boiling point: bp13 181°; bp2 142°; bp0.5 135°
Index of refraction: nD25 1.5519 to 1.5521
Density: d 1.0081
 
Derivative Type: Maleate
CAS Registry Number: 132-20-7
Trademarks: Avil (Aventis); Daneral (Aventis); Inhiston (Biomed. Foscama); Trimeton (Schering)
Molecular Formula: C16H20N2.C4H4O4
Molecular Weight: 356.42
Percent Composition: C 67.40%, H 6.79%, N 7.86%, O 17.96%
Properties: Crystals from amyl alcohol, faint amine-like odor, mp 107°. Freely sol in water, alcohol. Slightly sol in ether, benzene. pH of 1% aq soln between 4.3 and 4.9.
Melting point: mp 107°
 
Derivative Type: p-Aminosalicylate
CAS Registry Number: 3269-83-8
Molecular Formula: C16H20N2.C7H7NO3
Molecular Weight: 393.48
Percent Composition: C 70.21%, H 6.92%, N 10.68%, O 12.20%
Properties: Small needles from acetone + ethyl acetate, large octahedra from water, dec 142°. One gram dissolves in 10 ml water, freely sol in alcohol. Sparingly sol in ethyl acetate, ether, acetone.
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Alkylamine Derivatives.