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CAS No 84611-23-4 , 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid

  • Name: 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid
  • Synonyms: Erdosteinum [Latin]; NCGC00185774-01;84611-23-4; RV 144;2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid; PV 144; Erdosteine [INN]; Erdosteine (INN); RV-144;
  • CAS Registry Number:
  • Melting Point: 156-160 ºC
  • Density: 1.48 g/cm3
  • Molecular Weight: 249.30724
  • InchiKey: QGFORSXNKQLDNO-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H11NO4S2/c10-6(3-14-4-7(11)12)9-5-1-2-15-8(5)13/h5H,1-4H2,(H,
    9,10)(H,11,12)
  • Molecular Formula: C8H11NO4S2
  • Molecular Structure:CAS No:84611-23-4 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid
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84611-23-4 Erdosteine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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84611-23-4 Erdosteine

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84611-23-4 Erdosteine

  • Erdosteine[[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino] ethyl]thio]acetic acid, 99.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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84611-23-4 Erdosteine

  • Erdosteine
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
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84611-23-4 Erdosteine

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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84611-23-4 Erdosteine

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84611-23-4 Erdosteine

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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84611-23-4 Erdosteine

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China null,nullChina
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84611-23-4 Erdosteine

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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84611-23-4 Erdosteine

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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References of 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid
Title: Erdosteine
CAS Registry Number: 84611-23-4
CAS Name: [[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]acetic acid
Synonyms: (±)-[[[(tetrahydro-2-oxo-3-thienyl)carbamoyl]methyl]thio]acetic acid; DL-S-[2-[N-3-(2-oxotetrahydrothienyl)acetamido]]thioglycolic acid; N-(carboxymethylthioacetyl)homocysteine thiolactone; dithiosteine
Manufacturers' Codes: RV-144
Trademarks: Secresolv (Refarmed)
Molecular Formula: C8H11NO4S2
Molecular Weight: 249.31
Percent Composition: C 38.54%, H 4.45%, N 5.62%, O 25.67%, S 25.72%
Literature References: Homocysteine thiolactone derivative with mucomodulating activity. Prepn: J. Gonella, EP 61386; idem, US 4411909 (1982, 1983 both to Refarmed); M. Gobetti et al., Farmaco Ed. Sci. 41, 69 (1986). Clinical trial in bronchitis: G. Ricevuti et al., Thorax 43, 585 (1988). Clinical effect on a1-antitrypsin levels in cigarette smokers: M. Vagliasindi, G. B. Fregnan, Int. J. Clin. Pharmacol. Ther. Toxicol. 27, 238 (1989).
Properties: Crystals from ethanol, mp 156-158°. pKa 3.71. LD50 in mice and rats (g/kg): >10 orally; >3.5 i.v. (Gonella).
Melting point: mp 156-158°
pKa: pKa 3.71
Toxicity data: LD50 in mice and rats (g/kg): >10 orally; >3.5 i.v. (Gonella)
Therap-Cat: Mucolytic.
Keywords: Mucolytic.