Title: Bucolome
CAS Registry Number: 841-73-6
CAS Name: 5-Butyl-1-cyclohexyl-2,4,6(1
H,3
H,5
H)pyrimidinetrione
Synonyms: 5-butyl-1-cyclohexylbarbituric acid; 5-
n-butyl-1-cyclohexyl-2,4,6-trioxoperhydropyrimidine; BCP
Trademarks: Paramidin (Takeda)
Molecular Formula: C14H22N2O3
Molecular Weight: 266.34
Percent Composition: C 63.13%, H 8.33%, N 10.52%, O 18.02%
Literature References: Prepn: Senda
et al., US 3243344 and
US 3274195 (both 1966 to Takeda). Metabolic studies in man: Yashiki
et al., Chem. Pharm. Bull. 19, 468, 869 (1971).
Properties: Needles from methanol, mp 84°. bp0.8 185-187°.
Melting point: mp 84°
Boiling point: bp0.8 185-187°
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal).