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CAS No 84088-42-6 , 4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide

  • Name: 4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide
  • Synonyms: 84088-42-6; PNU-212616; Roquinimexum [Latin]; LS-2616; DSSTox_CID_25680;4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide;Linomide; FCF-89; CCRIS 7673; ROQUINIMEX; NCGC00025172-01;
  • CAS Registry Number:
  • Transport: UN 2811
  • Flash Point: 217.598°C
  • Boiling Point: 436.187°C at 760 mmHg
  • Density: 1.357g/cm3
  • Refractive index: 1.686
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 217.598°C
  • Molecular Weight: 308.33124
  • InchiKey: SGOOQMRIPALTEL-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H16N2O3/c1-19(12-8-4-3-5-9-12)17(22)15-16(21)13-10-6-7-11-14
    (13)20(2)18(15)23/h3-11,21H,1-2H3
  • Risk Statements: S36/37
  • Molecular Formula: C18H16N2O3
  • Molecular Structure:CAS No:84088-42-6 4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide

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84088-42-6 LINOMIDE

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84088-42-6 Roquinimex

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84088-42-6 Roquinimex, 99%

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84088-42-6 1,2-Dihydro-4-hydroxy-N,N-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide

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References of 4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide
Title: Roquinimex
CAS Registry Number: 84088-42-6
CAS Name: 1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide
Synonyms: N-phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide; 1,2-dihydro-4-hydroxy-N,1-dimethyl-2-oxo-3-quinolinecarboxanilide
Manufacturers' Codes: LS-2616
Trademarks: Linomide (Pfizer)
Molecular Formula: C18H16N2O3
Molecular Weight: 308.33
Percent Composition: C 70.12%, H 5.23%, N 9.09%, O 15.57%
Literature References: Biological response modifier. Prepn: E. Eriksoo et al., EP 59698; eidem, US 4738971 (1982, 1988 both to AB Leo). Immunopharmacology: A. Tarkowski et al., Immunology 59, 589 (1986). Mechanism of action study: E.-L. Larsson et al., Int. J. Immunopharmacol. 9, 425 (1987). Clinical evaluation in cancer patients: J. C. S. Bergh et al., Cancer Invest. 15, 204 (1997).
Properties: Crystals from pyridine, mp 200-204°.
Melting point: mp 200-204°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Immunomodulators.