Title: Iodoquinol
CAS Registry Number: 83-73-8
CAS Name: 5,7-Diiodo-8-quinolinol
Synonyms: diiodohydroxyquin; diiodo-oxyquinoline; 5,7-diiodo-8-hydroxyquinoline
Manufacturers' Codes: SS-578
Trademarks: Diodoquin (Searle); Disoquin; Floraquin (Searle); Dyodin; Dinoleine; Searlequin; Diodoxylin; Rafamebin; Ioquin (Abbott); Direxiode (Delalande); Stanquinate; Yodoxin (Searle); Zoaquin; Enterosept; Embequin (M & B)
Molecular Formula: C9H5I2NO
Molecular Weight: 396.95
Percent Composition: C 27.23%, H 1.27%, I 63.94%, N 3.53%, O 4.03%
Literature References: Prepd by the action of iodine monochloride on 8-hydroxyquinoline: Papesch, Burtner,
J. Am. Chem. Soc. 58, 1314 (1936); by the action of KIO3 on 8-hydroxyquinoline: Zeifman,
C.A. 34, 3745. Electrolytic prepn: Brown, Berkowitz,
Trans. Electrochem. Soc. 75, 385 (1939).
See also Claus,
DE 78880; Passek,
DE 411050; Matsumura,
C.A. 21, 1461 (1927); Pirrone, Cherubino,
C.A. 28, 3073 (1934).
Properties: Crystals from xylene. The medicinal grade is a yellowish-brown powder. mp 200-215° (extensive decompn). Almost insol in water. Sparingly sol in alcohol, ether, and acetone; sol in hot pyridine and in hot dioxane.
Melting point: mp 200-215° (extensive decompn)
Therap-Cat: Antiamebic.
Keywords: Antiamebic.