Home > Name List By 2 > 2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N, N-dipropylacetamide

CAS No 82626-01-5 , 2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,
N-dipropylacetamide

  • Name: 2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,
    N-dipropylacetamide
  • Synonyms: DSSTox_GSID_49046; SL 80.0342-00; Alpidemum [Latin]; DSSTox_CID_28972;2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,
    N-dipropylacetamide;Ananxyl; 82626-01-5; DSSTox_RID_83237; NCGC00182850-01;
  • CAS Registry Number:
  • Density: 1.24g/cm3
  • Refractive index: 1.606
  • Molecular Weight: 404.33282
  • InchiKey: JRTIDHTUMYMPRU-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H23Cl2N3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-7-16(22)8-6-
    15)24-19-10-9-17(23)14-26(18)19/h5-10,14H,3-4,11-13H2,1-2H3
  • Molecular Formula: C21H23Cl2N3O
  • Molecular Structure:CAS No:82626-01-5 2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,<br />N-dipropylacetamide

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References of 2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,
N-dipropylacetamide
Title: Alpidem
CAS Registry Number: 82626-01-5
CAS Name: 6-Chloro-2-(4-chlorophenyl)-N,N-dipropylimidazo[1,2-a]pyridine-3-acetamide
Manufacturers' Codes: SL-80.0342
Trademarks: Ananxyl (Synthelabo)
Molecular Formula: C21H23Cl2N3O
Molecular Weight: 404.33
Percent Composition: C 62.38%, H 5.73%, Cl 17.54%, N 10.39%, O 3.96%
Literature References: Non-benzodiazepine tranquilizer. Prepn: J. P. Kaplan, P. George, EP 50563; eidem, US 4382938 (1982, 1983 both to Synthelabo). Pharmacology and pharmacokinetics in humans: B. Saletu et al., Int. Clin. Psychopharmacol. 1, 145 (1986). HPLC determn in human plasma: V. Ascalone et al., J. Chromatogr. 414, 101 (1987). Clinical evaluation of tranquilizing vs hypnotic effects: B. Saletu et al., Curr. Ther. Res. 40, 769 (1986). Pilot study in anxiety: S. F. Langer et al., Psychopharmacol. Bull. 24, 161 (1988). Hepatotoxicity in rats: A. Berson et al., J. Pharmacol. Exp. Ther. 299, 793 (2001).
Properties: mp 140-141°.
Melting point: mp 140-141°
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.