Home > Name List By 2 > 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene- 1,3-thiazolidin-3-yl]acetic acid China

CAS No 82159-09-9 , 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-
1,3-thiazolidin-3-yl]acetic acid Search by region : China

  • Name: 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-
    1,3-thiazolidin-3-yl]acetic acid
  • Synonyms: Ono-2235; Epalrestat [INN]; ONO 2;2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-
    1,3-thiazolidin-3-yl]acetic acid; Epalrestatum; Epalrestatum [Latin]; Ono 2235;Kinedak; ONO-2; 82159-09-9;
  • CAS Registry Number:
  • Melting Point: 210-217 ºC
  • Flash Point: 266.4 ºC
  • Boiling Point: 516.8 ºC at 760 mmHg
  • Density: 1.43 g/cm3
  • Refractive index: 1.705
  • Water Solubility: Soluble in water
  • Flash Point: 266.4 ºC
  • Molecular Weight: 319.39862
  • InchiKey: CHNUOJQWGUIOLD-NFZZJPOKSA-N
  • InChI: InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15
    (20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8-
  • Molecular Formula: C15H13NO3S2
  • Molecular Structure:CAS No:82159-09-9 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-<br />1,3-thiazolidin-3-yl]acetic acid

Related products

Select to

82159-09-9 Epalrestat

  • Name(En): Epalrestat CAS: 82159-09-9 WeightFrag: 319.4 Assay/specification: 98% Purpose: Aldose reductase inhibitor, can reversibly inhibit the conversion of glucose to sorbitol aldose reductase activity and its mechanism. For symptoms, the obstacles...
  • China Suzhou Yacoo science Corporation [Manufacturer]
  • Tel: 86-0512-87666785
  • Fax: 86-0512-87182056
  • Address: 17 Jinahi RD Suzhou Industrial Park China Suzhou,JiangsuChina
Contact Supplier

yab126
  • i

    • 82159-09-9 epalrestat

    • China Taiyuan RHF CO., ltd. [Manufacturers]
    • Tel: 0351-7436719
    • Fax: +86-351-7436719
    • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
    Contact Supplier

    82159-09-9 epalrestat

    Contact Supplier

    82159-09-9 Epalrestat

    • China Ahk Tech Inc. [Trading Company]
    • Tel: 86-0519-88222336
    • Fax: 86-0519-88222335
    • Address: Room 447, Hi-Tech Park, Xinbei District Changzhou,JiangsuChina
    Contact Supplier

    82159-09-9 Clometerone

    • Clometerone, Min 99%
    • China Finechemie Co., Ltd. [Manufacturer]
    • Tel: +86-23-99186710
    • Fax: +86-23-99186729
    • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
    Contact Supplier

    82159-09-9 epalrestat

    • China YiPeng Chemical [Manufacturers]
    • Tel: 571 85376369
    • Fax: 571 88233092
    • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
    Contact Supplier

    82159-09-9 Epalrestat

    Contact Supplier

    82159-09-9 Epalrestat

    • China Ningbo Inno Pharmchem Co., Ltd. [Manufacturers]
    • Tel: +86-(574)-87319282
    • Fax: +86-(574)-56877908
    • Address: 5F, Building 4, 1035 Guangxian Rd., Ningbo Hi-Tech Park, Ningbo, Zhejiang 315040, Ningbo,ZhejiangChina
    Contact Supplier

    82159-09-9 epalrestat

    • China Wuxi Mizat Chemical Technology Co., Ltd. [Manufacturer]
    • Tel: +86-510-86106900/ +86-510-86125752
    • Fax: +86-510-86125752
    • Address: No.205,zhencheng Road,
      HI-TECT District,
      Wuxi, Jiangsu,China null,nullChina
    Contact Supplier

    82159-09-9 Epalrestat

    • China Watson International Ltd. null
    • Tel: +86-(512)-55117610
    • Fax: +86-(512)-55117630
    • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
    Contact Supplier

    Select to

    1/7
    1 2 3 4 5 6 7 Next
    References of 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-
    1,3-thiazolidin-3-yl]acetic acid
    Title: Epalrestat
    CAS Registry Number: 82159-09-9
    CAS Name: (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid
    Synonyms: 5-[(E,E)-b-methylcinnamylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-carboxymethyl-5-(2-methylcinnamylidene)rhodanine
    Manufacturers' Codes: ONO-2235
    Trademarks: Kinedak (Ono); Sorbistat (Ono)
    Molecular Formula: C15H13NO3S2
    Molecular Weight: 319.40
    Percent Composition: C 56.41%, H 4.10%, N 4.39%, O 15.03%, S 20.08%
    Literature References: Aldose reductase inhibitor. Prepn: T. Tadao et al., EP 47109; eidem, US 4464382 (1982, 1984 both to Ono Pharmaceutical). Inhibitory effect on aldose reductase in vitro: H. Terashima et al., J. Pharmacol. Exp. Ther. 229, 226 (1983). Effect on motor nerve conduction and sorbitol levels in diabetic rats: R. Kikkawa et al., Diabetologia 24, 290 (1983). Effect in rats on peripheral nerve dysfunction: eidem, Metabolism 33, 212 (1984); on retinal microangiopathy: K. Kojima et al., Jpn. J. Ophthalmol. 29, 99 (1985).
    Properties: Crystals from ethanol-water, mp 210-217°.
    Melting point: mp 210-217°
     
    Derivative Type: N-Methyl-D-glucamine salt
    Molecular Formula: C22H30N2O8S2
    Molecular Weight: 514.61
    Percent Composition: C 51.35%, H 5.88%, N 5.44%, O 24.87%, S 12.46%
    Properties: Crystals from methanol, mp 163-165°.
    Melting point: mp 163-165°
     
    Therap-Cat: Treatment of diabetic neuropathy.
    Keywords: Aldose Reductase Inhibitor.