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CAS No 81131-70-6 , Pravastatin sodium

  • Name: Pravastatin sodium
  • Synonyms: Pravastatin sodium;Pravastatin Sodium; [1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic acid monosodium salt;Pravastatin sodium salt;
  • CAS Registry Number:
  • Transport: 3077
  • Melting Point: 154-160 ºC
  • Flash Point: 213.2 ºC
  • Boiling Point: 634.5ºCat 760 mmHg
  • Water Solubility: H2O: 19 mg/mL in water
  • Safety Statements: Moderately toxic by intravenous and intraperitoneal. Low toxicity by ingestion. Human systemic effects. When heated to decomposition it emits acrid smoke and irritating vapors.
  • Hazard Symbols: F: Flammable;C: Corrosive;
  • Flash Point: 213.2 ºC
  • Molecular Weight: 446.52
  • InChI: InChI=1/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
  • Risk Statements: 11-34
  • Molecular Formula: C23H35NaO7
  • Molecular Structure:CAS No:81131-70-6 Pravastatin sodium
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81131-70-6 81131-70-6 & Pravastatin sodium

  • Product Name:Pravastatin sodium Certification:ISO9001 CAS: 81131-70-6 MF: C23H36NaO7 MW: 447.52 Assay: 99% Standard: enterprise Standard Packaging : 25kg/drum or according to customer's requirement Payment Terms:L/C or T/T ,Bank Transfer and WU. Deli...
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  • China Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd [Manufacturer, Trading Company]
  • Tel: 86-027-50755950
  • Fax: 86-027-88048077
  • Address: No. 496, Zhongshan Road, Wuchang District, Wuhan 430064, China. Wuhan,HebeiChina
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81131-70-6 Pravastatin Sodium (US Pat 1981)

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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81131-70-6 Pravastatin Sodium

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81131-70-6 Pravastatin Sodium (US Pat 1981)

  • China Simag Chemicals [Manufacturer]
  • Tel: +86 592 2680277
  • Fax: +86 592 2680237
  • Address: Simag Chemicals
    A-9D Atlantic sea view city,
    No.9 Hubin West Rd.,
    Xiamen China. ,China
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81131-70-6 PRAVASTATIN SODIUM

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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81131-70-6 Pravastatin Sodium

  • China Facus Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-6237-8411
  • Fax: +86-(574)-6237-8410
  • Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800, Ningbo,ZhejiangChina
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81131-70-6 PRAVASTATIN SODIUM

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
  • Fax: 86-571-81956190 88386326
  • Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China. Hangzhou,ZhejiangChina
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81131-70-6 Pravastatin Sodium

  • United States Tecoland Corporation []
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, ,United States
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81131-70-6 PRAVASTATIN SODIUM

  • United States NetQem, LLC [Manufacturer]
  • Tel: (919) 544-4122
  • Fax: (919) 544-4109
  • Address: NetQem, LLC
    P.O. Box 12091
    Research Triangle Park
    NC 27709, USA ,United States
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81131-70-6 PRAVASTATIN SODIUM(RG)

  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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References of Pravastatin sodium
Title: Pravastatin Sodium
CAS Registry Number: 81131-70-6
CAS Name: (bR,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt
Synonyms: sodium (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoate; eptastatin sodium; 3b-hydroxycompactin sodium salt
Manufacturers' Codes: CS-514; SQ-31000
Trademarks: Elisor (BMS); Lipostat (BMS); Liprevil (Schwarz); Mevalotin (Sankyo); Oliprevin (BMS); Pravachol (BMS); Pravaselect (Menarini); Pravasin (BMS); Selectin (BMS); Selipran (BMS); Vasten (Specia)
Molecular Formula: C23H35NaO7
Molecular Weight: 446.51
Percent Composition: C 61.87%, H 7.90%, Na 5.15%, O 25.08%
Literature References: HMG-CoA reductase inhibitor; bioactive metabolite of mevastatin, q.v. Prepn by microbial hydroxylation: A. Terahara, M. Tanaka, DE 3122499; eidem, US 4346227 (1981, 1982 both to Sankyo); N. Serizawa et al., J. Antibiot. 36, 604 (1983). Structure elucidation: H. Haruyama et al., Chem. Pharm. Bull. 34, 1459 (1986). HPLC determn in biological fluids: S. Bauer et al., J. Chromatogr. B 818, 257 (2005). Effect on serum lipid concentration: N. Nakaya et al., Atherosclerosis 61, 125 (1986); on hepatic metabolism of cholesterol: E. Reihnér et al., N. Engl. J. Med. 323, 224 (1990). Clinical comparison with probucol, q.v.: G. Yoshino et al., Lancet 2, 740 (1986). Clinical reduction of risk of major cardiovascular events in patients with coronary heart disease: LIPID Study Group, N. Engl. J. Med. 339, 1349 (1998). Clinical effect on risk of stroke: H. D. White et al., ibid. 343, 317 (2000).
Properties: Odorless, white to off-white, fine or crystalline powder. uv max (methanol): 230, 237, 245 nm. Sol in methanol, water; slightly sol in isopropanol. Practically insol in acetone, acetonitrile, chloroform, ether.
Absorption maximum: uv max (methanol): 230, 237, 245 nm
 
Derivative Type: Lactone
Molecular Formula: C23H34O6
Molecular Weight: 406.51
Percent Composition: C 67.96%, H 8.43%, O 23.61%
Properties: Colorless plate crystals, mp 138-142°. [a]D22 +194.0° (c = 0.51 in methanol). uv max (methanol): 230, 237, 245 nm.
Melting point: mp 138-142°
Optical Rotation: [a]D22 +194.0° (c = 0.51 in methanol)
Absorption maximum: uv max (methanol): 230, 237, 245 nm
 
Therap-Cat: Antilipemic.
Keywords: Antilipemic; HMG CoA Reductase Inhibitors; HMG CoA Reductase Inhibitor.