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CAS No 81-25-4 , Cholic acid

  • Name: Cholic acid
  • Synonyms: Cholic acid; Cholan-24-oic acid;3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 197-202 ºC
  • Flash Point: 321°C
  • Boiling Point: 545
  • Density: 1.184g/cm3
  • Refractive index: 1.558
  • Alpha: 36 º (C=0.6, 95% ETOH)
  • Water Solubility: 0.28 G/L (15 ºC)
  • Safety Statements: S24/25
  • Hazard Symbols: UN NO.
  • Flash Point: 321°C
  • EINECS: 201-337-8
  • Molecular Weight: 408.58
  • InChI: InChI=1/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1
  • Risk Statements: S24/25
  • Molecular Formula: C24H40O5
  • Molecular Structure:CAS No:81-25-4 Cholic acid
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81-25-4 Cholic acid

  • Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Payment & Shipping Terms: Price: Minimum Order Quantity:1kg Supply Ability:500kg/month Delivery Time:within 24 hours after payment Payment Terms:Western Union, MoneyGram, ...
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer, Trading Company]
  • Tel: 86-027-50756185
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  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
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  • 81-25-4 Cholic acid

    • White crystal, 98%min
    • China Hangzhou Dingyan Chem Co.,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
    • Tel: 86-571-88025800
    • Fax: 86-571-87156470
    • Address: Xiasha 571, 19TH Street E-COMMERCE 4A 601-602 , Jianggan Area hangzhou,ZhejiangChina

    81-25-4 Cholic acid

    • Product Name: Cholic acid Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Payment & Shipping Terms: Price: Minimum Order Quantity:1kg Supply Ability:500kg/month Delivery Time:within 24 hours after payment Payment Terms:...
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    • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer]
    • Tel: 86-181-88938010
    • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
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    81-25-4 Cholic acid

    • Product Name: Cholic acid Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Payment & Shipping Terms: Price: Minimum Order Quantity:1kg Supply Ability:500kg/month Delivery Time:within 24 hours after payment Payment Terms:...
    • Min. Order: 25
    • FOB Price: USD1 - 1 /
    • China Zhuzhou Yuancheng Hezhong Technology Development C [Manufacturer]
    • Tel: 86-027-50756060
    • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
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    81-25-4 Cholic Acid

    • China Chemrio International Limited [Manufacturer]
    • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
    • Fax: +86 574 2789 1266
    • Address: Chemrio International Limited
      Room 611-612, Wante Business Center
      No.487 Yangmuqi Road,
      Hi-tech Park Ningbo, 315040,China null,nullChina
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    81-25-4 Cholic acid

    • Cholic acid
    • United States INDOFINE Chemical Co., Inc. [Manufacturer]
    • Tel: (908) 359-6778
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    • Address: 121 Stryker Lane
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    81-25-4 Orazamide

    • OrazamideOrazamide, 98%
    • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
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    • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
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    81-25-4 Orazamide

    • Orazamide, 98%
    • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
    • Tel: +86-21-64968086
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    • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
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    81-25-4 Cholic acid

    • Cholic acid
    • Hong kong Frapp's Pharma (Hongkong) Co.,Ltd [Manufacturer]
    • Tel: +852 8130 0917
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    • Address: Room 801,Mongkok Harbour Centre,638 Shanghai Street,Mongkok,Kowloon,Hongkang518001 MongkokHONG KONG Mongkok,nullHong kong
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    81-25-4 Cholic acid

    • Cholic acid
    • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
    • Tel: +86-28-88007744
    • Fax: +86-28-85193812
    • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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    References of Cholic acid
    Title: Cholic Acid
    CAS Registry Number: 81-25-4
    CAS Name: (3a,5b,7a,12a)-3,7,12-Trihydroxycholan-24-oic acid
    Synonyms: cholalic acid; 17b-(1-methyl-3-carboxypropyl)etiocholane-3a,7a,12a-triol
    Trademarks: Colalin
    Molecular Formula: C24H40O5
    Molecular Weight: 408.57
    Percent Composition: C 70.55%, H 9.87%, O 19.58%
    Literature References: Occurs in conjugation with glycine or taurine in bile of most vertebrates. Extraction from beef bile: Wieland, Siebert, Z. Physiol. Chem. 262, 1 (1939); laboratory procedure: Gattermann-Wieland, Praxis des Organischen Chemikers (de Gruyter, Berlin, 40th ed., 1961) p 360. Structure and synthesis: Fieser, Fieser, Steroids (Reinhold, New York, 1959).
     
    Derivative Type: Monohydrate
    Properties: Plates from dil acetic acid. Bitter taste with sweetish aftertaste. When anhydr, mp 198°. [a]D20 +37° (c = 0.6 in alcohol). pK = 6.4. Not precipitated by digitonin. Soly at 15° in water 0.28 g/l; in alcohol 30.56 g/l; in ether 1.22 g/l; in chloroform 5.08 g/l; in benzene 0.36 g/l; in acetone 28.24 g/l; in glacial acetic acid 152.12 g/l. Sol in solns of alkali hydroxides or carbonates.
    Melting point: mp 198°
    pKa: pK = 6.4
    Optical Rotation: [a]D20 +37° (c = 0.6 in alcohol)
     
    Derivative Type: Methyl ester
    Molecular Formula: C25H42O5
    Molecular Weight: 422.60
    Percent Composition: C 71.05%, H 10.02%, O 18.93%
    Properties: Crystals from 95% alcohol + water, mp 155-156°.
    Melting point: mp 155-156°
     
    Derivative Type: Ethyl ester
    Molecular Formula: C26H44O5
    Molecular Weight: 436.62
    Percent Composition: C 71.52%, H 10.16%, O 18.32%
    Properties: Crystals from ethyl acetate + petr ether, mp 162-163°.
    Melting point: mp 162-163°
     
    Derivative Type: Sodium salt
    Synonyms: Sodium cholate
    Molecular Formula: C24H39NaO5
    Molecular Weight: 430.55
    Percent Composition: C 66.95%, H 9.13%, Na 5.34%, O 18.58%
    Properties: Crystals. Soly in water at 15°: >568.9 g/l.
     
    CAUTION: The names "sodium cholate" and "sodium choleate" are sometimes used for mixtures of bile salts. The term "sodium choleate" is to be preferred for bile salts, see Ox Bile Extract.
    NOTE: The property of forming molecular compds is common to bile acids. For instance a blue molecular compd (C24H40O5I)4.KI.H2O, may be prepd by mixing an alcoholic soln of cholic acid and a soln of iodine in aq potassium iodide: Barger, Field, J. Chem. Soc. 101, 1404 (1912).
    Therap-Cat: Choleretic.
    Keywords: Choleretic.