Home > Name List By other > (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3, 12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide

CAS No 808-26-4 , (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,
12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide

  • Name: (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,
    12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
  • Synonyms: Sanciclina; Bonomycin; Bonomycin (TN);(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,
    12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide; SANCICLINE;Norcycline; NSC51812; Sancyclinum; 808-26-4; GS 2147;
  • CAS Registry Number:
  • Melting Point: 224-2280C (dec)
  • Flash Point: 750.9 °C at 760 mmHg
  • Boiling Point: 750.9 °C at 760 mmHg
  • Density: 1.61 g/cm3
  • Refractive index: 1.734
  • Flash Point: 750.9 °C at 760 mmHg
  • Molecular Weight: 414.40858
  • InchiKey: MTCQOMXDZUULRV-ADOAZJKMSA-N
  • InChI: InChI=1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18
    (27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24-25,28,30H,6-7H2,
    1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
  • Molecular Formula: C21H22N2O7
  • Molecular Structure:CAS No:808-26-4 (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,<br />12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide

Related products

Search by region :

Select to

808-26-4 SANCYCLINE

  • Germany Archimica [Manufacturer]
  • Tel: +49 (0)69 / 305-25866
  • Fax: +49 (0)69 / 305-17562
  • Address: Archimica
    Industriepark Hoechst, D 569
    65926 Frankfurt/Main, Germany null,nullGermany
Contact Supplier

808-26-4 SANCYCLINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,
12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
Title: Sancycline
CAS Registry Number: 808-26-4
CAS Name: [4S-(4a,4aa,5aa,12aa)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
Synonyms: 6-demethyl-6-deoxytetracycline; norcycline
Trademarks: Bonomycin (Pfizer)
Molecular Formula: C21H22N2O7
Molecular Weight: 414.41
Percent Composition: C 60.86%, H 5.35%, N 6.76%, O 27.03%
Literature References: Semi-synthetic antibiotic related to tetracycline. Prepn: Beereboom et al., J. Am. Chem. Soc. 82, 1003 (1960); McCormick et al., ibid. 3381; McCormick, Jensen, US 3019260 (1962 to Am. Cyanamid); GB 901209 (1962 to Pfizer). Total synthesis: Conover et al., J. Am. Chem. Soc. 84, 3222 (1962).
 
Derivative Type: Hydrochloride hemihydrate
Molecular Formula: C21H22N2O7.HCl.?H2O
Molecular Weight: 459.88
Percent Composition: C 54.85%, H 5.26%, N 6.09%, O 26.09%, Cl 7.71%
Properties: Crystals from ethanol, dec 215-220°. uv max (MeOH/0.01N HCl): 267, 347 nm (e 19300, 15500); in 0.1N H2SO4: 217, 268, 343 nm (e 13400, 19000, 14600).
Absorption maximum: uv max (MeOH/0.01N HCl): 267, 347 nm (e 19300, 15500); in 0.1N H2SO4: 217, 268, 343 nm (e 13400, 19000, 14600)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Tetracyclines.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.