Home > Name List By 2 > 2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic acid

CAS No 80576-83-6 , 2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic
acid

  • Name: 2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic
    acid
  • Synonyms: Edatrexato [INN-Spanish]; EDATREXATE; 10-Ethyl-10-deazaaminopterin;2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic
    acid;10-EdAM; Edatrexatum [INN-Latin]; 80576-83-6;
  • CAS Registry Number:
  • Density: 1.441 g/cm3
  • Refractive index: 1.686
  • Molecular Weight: 467.4778
  • InchiKey: FSIRXIHZBIXHKT-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H25N7O5/c1-2-11(9-14-10-25-19-17(26-14)18(23)28-22(24)29-19)
    12-3-5-13(6-4-12)20(32)27-15(21(33)34)7-8-16(30)31/h3-6,10-11,15H,2,
    7-9H2,1H3,(H,27,32)(H,30,31)(H,33,34)(H4,23,24,25,28,29)
  • Molecular Formula: C22H25N7O5
  • Molecular Structure:CAS No:80576-83-6 2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic<br />acid

Related products

Search by region :

Select to

80576-83-6 EDATREXATE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

80576-83-6 Edatrexate

  • Edatrexate, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

80576-83-6 Edatrexate

  • Edatrexate, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

80576-83-6 Psyllium Seed

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

80576-83-6 Edatrexate, 99%

  • Edatrexate, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
Contact Supplier

80576-83-6 L-Glutamic acid,N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]propyl]benzoyl]-

  • China Shanghai Hao Su Chem-Tech lnc. [Manufacturers]
  • Tel: 021-6661 0036 021-5653 8833
  • Fax: (86 21) 5653 3269
  • Address: 201-204,2 BLDG,1009 North Zhong Shan Road, Shanghai Shanghai,ShanghaiChina
Contact Supplier

80576-83-6 Psyllium Seed

  • India Rama Industries null
  • Tel: +91-(2744)-226761, 226093
  • Fax: +91-(2744)-226494
  • Address: Near G.I.D.C,Patan Highway Road, Deesa, Gujarat 385535, null,nullIndia
Contact Supplier

80576-83-6 Psyllium Seed

  • India Altrafine Gums [Manufacturers]
  • Tel: +91-(79)-2589-0401, 2583 0469
  • Fax: +91-(79)-2589 0406, 2583 3148
  • Address: 88/2, G.I.D.C. Estate, Phase - 1, Near Jindal Char Rasta, Vatva, Ahmedabad, Gujarat 382 445, AHMEDABAD,GUJARATIndia
Contact Supplier

80576-83-6 EDATREXATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic
acid
Title: Edatrexate
CAS Registry Number: 80576-83-6
CAS Name: N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]propyl]benzoyl]-L-glutamic acid
Synonyms: 10-ethyl-10-deazaaminopterin; 10-EdAM; 10-EDAAM
Manufacturers' Codes: CGP-30694
Molecular Formula: C22H25N7O5
Molecular Weight: 467.48
Percent Composition: C 56.52%, H 5.39%, N 20.97%, O 17.11%
Literature References: Dihydrofolate reductase inhibitor. Prepn: F. M. Sirotnak, J. I. DeGraw, FR 2464956 (1981 to SRI International); J. I. DeGraw, Jr., F. M. Sirotnak, US 4369319 (1983). Synthesis: J. I. DeGraw et al., J. Med. Chem. 25, 1227 (1982); and resolution of diastereomers: eidem, ibid. 29, 1056 (1986). HPLC determn: J. J. Kinahan et al., Anal. Biochem. 150, 203 (1985); O. Van Tellingen et al., J. Chromatogr. 529, 135 (1990). Pharmacology and toxicology: M. P. Fanucchi et al., Cancer Res. 47, 2334 (1987). Clinical evaluation in non-small cell lung cancer: J. S. Lee et al, Invest. New Drugs 8, 299 (1990). Review of pharmacology and antitumor activity: F. M. Sirotnak et al., NCI Monogr. 5, 127-131 (1987).
Properties: Prepd as 1.75 H2O, uv max (pH 13): 255, 370 nm (e 30731, 7582).
Absorption maximum: uv max (pH 13): 255, 370 nm (e 30731, 7582)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Folic Acid Analogs/Antagonists.