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CAS No 800-22-6 , 1-(2-chlorophenothiazin-10-yl)-3-(diethylamino)propan-1-one

  • Name: 1-(2-chlorophenothiazin-10-yl)-3-(diethylamino)propan-1-one
  • Synonyms: Chloroacyzin; Chloroacizine;1-(2-chlorophenothiazin-10-yl)-3-(diethylamino)propan-1-one; Chloroacizin; Chlorazicine; Chlorazicin;CHLORACYZINE; Chloracizinum; Chloracizin; Chloracyzine [INN:DCF];
  • CAS Registry Number:
  • Flash Point: 288.8°C
  • Boiling Point: 553.9°C at 760 mmHg
  • Density: 1.246g/cm3
  • Refractive index: 1.621
  • Flash Point: 288.8°C
  • Molecular Weight: 360.90084
  • InchiKey: ZZKWNLZUYAGVOT-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H21ClN2OS/c1-3-21(4-2)12-11-19(23)22-15-7-5-6-8-17(15)24-18-
    10-9-14(20)13-16(18)22/h5-10,13H,3-4,11-12H2,1-2H3
  • Molecular Formula: C19H21ClN2OS
  • Molecular Structure:CAS No:800-22-6 1-(2-chlorophenothiazin-10-yl)-3-(diethylamino)propan-1-one

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References of 1-(2-chlorophenothiazin-10-yl)-3-(diethylamino)propan-1-one
Title: Chloracizine
CAS Registry Number: 800-22-6
CAS Name: 2-Chloro-10-[3-(diethylamino)-1-oxopropyl]-10H-phenothiazine
Synonyms: 2-chloro-10-(N,N-diethyl-b-alanyl)phenothiazine; 10-(b-diethylaminopropionyl)-2-chlorophenothiazine; 2-chloro-10-(b-diethylaminopropionyl)phenothiazine; chloracysin; chlorocyzine; chlorocizin; khloratsizin
Manufacturers' Codes: G-020
Molecular Formula: C19H21ClN2OS
Molecular Weight: 360.90
Percent Composition: C 63.23%, H 5.86%, Cl 9.82%, N 7.76%, O 4.43%, S 8.88%
Literature References: Prepn: Horclois, Metivier, FR 1060715 (1954 to Rh?ne Poulenc); GB 740932 (1955); Zhuravlev, Gritsenko, Zh. Obshch. Khim. 26, 3385 (1956), C.A. 51, 9623h (1957). For other prepns in Russian journals see C.A. 55, 6484b, 9425a (1961).
 
Derivative Type: Hydrochloride
Molecular Formula: C19H21ClN2OS.HCl
Molecular Weight: 397.36
Percent Composition: C 57.43%, H 5.58%, Cl 17.84%, N 7.05%, O 4.03%, S 8.07%
Properties: Crystals from isopropanol, mp 168-169°. Sol in water.
Melting point: mp 168-169°
 
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary).