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CAS No 50-53-3 , 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine

  • Name: 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
  • Synonyms: Aminazine;3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine; Contomin; Propaphenin; Chlorderazin; Chloropromazine; Fenactil; Megaphen; Thorazine;Largactil;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 192 - 196 C (decomposes)
  • Flash Point: 226°C
  • Boiling Point: 450.1°Cat760mmHg
  • Density: 1.212g/cm3
  • Water Solubility: Soluble
  • Hazard Symbols: 6.1 (Packing Group: III) UN NO.
  • Flash Point: 226°C
  • EINECS: 200-045-8
  • Molecular Weight: 318.86416
  • InchiKey: ZPEIMTDSQAKGNT-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13
    (18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
  • Molecular Formula: C17H19ClN2S
  • Molecular Structure:CAS No:50-53-3 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
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50-53-3 chlorpromazine

  • IUPAC NAME-3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-propan-1-amine MOLECULAR FORMULA-C17H19ClN2S MOLAR MASS-318.86 g/mol (free base) 355.33 g/mol (hydrochloride) Chlorpromazine is classified as a low-potency typical antipsychotic and in the p...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
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50-53-3 chlorpromazine

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50-53-3 chlorpromazine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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50-53-3 Chlorpromazine

  • Chlorpromazine
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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50-53-3 Chlorpromazine

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
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50-53-3 Chlorpromazine

  • Chlorpromazine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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50-53-3 Chlorpromazine

  • Chlorpromazine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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50-53-3 Chlorpromazine

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50-53-3 Chlorpromazine

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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50-53-3 Chlorpromazine

  • Chlorpromazine Chlorpromazine(Alkali)
  • Netherlands Vitas-M Laboratory [Manufacturer]
  • Tel: +31 (0)55 50 500 33
  • Fax: +31 (0)55 50 500 34
  • Address: PO Box 200477302 HA ApeldoornNETHERLANDS 7302 HA Apeldoorn,Netherlands
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References of 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
Title: Chlorpromazine
CAS Registry Number: 50-53-3
CAS Name: 2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine
Synonyms: 2-chloro-10-(3-dimethylaminopropyl)phenothiazine; 3-chloro-10-(3-dimethylaminopropyl)phenothiazine; N-(3-dimethylaminopropyl)-3-chlorophenothiazine
Manufacturers' Codes: 2601-A; HL-5746; RP-4560; SKF-2601-A
Molecular Formula: C17H19ClN2S
Molecular Weight: 318.86
Percent Composition: C 64.03%, H 6.01%, Cl 11.12%, N 8.79%, S 10.06%
Literature References: Prepn: Charpentier et al., Compt. Rend. 235, 59 (1952); Charpentier, US 2645640 (1953 to Rh?ne-Poulenc). Effects of neuroleptics on dopamine receptors: N.-E. Anden et al., Eur. J. Pharmacol. 11, 303 (1970). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Review of analytical methods for determn in pharmaceutical prepns: L. F. S. Chagonda, J. S. Millership, J. Pharm. Biomed. Anal. 7, 271-278 (1989). Brief historical review: G. Curzon, Trends Pharmacol. Sci. 11, 61-63 (1990).
Properties: Oily liq. Amine odor. Alkaline reaction. bp0.8 200-205°.
Boiling point: bp0.8 200-205°
 
Derivative Type: Hydrochloride
CAS Registry Number: 69-09-0
Trademarks: Ampliactil (Aventis); Amplictil (Aventis); Chloractil (DDSA); Chlorazin (Streuli); Contomin (Takeda); Fenactil (Jelfa); Hibernal (Aventis); Largactil (Aventis); Plegomazin (Servier); Promacid (CID); Promactil (Combiphar); Propaphenin (Rodleben); Prozin (Lusofarmaco); Taroctyl (Taro); Thorazine (GSK); Wintermin (Shionogi)
Molecular Formula: C17H19ClN2S.HCl
Molecular Weight: 355.33
Percent Composition: C 57.46%, H 5.67%, Cl 19.95%, N 7.88%, S 9.02%
Properties: Crystals, dec 179-180° (capillary); 194-196° (microblock). uv curve: Neuhoff, Auterhoff, Arch. Pharm. 288, 400 (1955). pH of 5% aq soln 4.0-5.5. One gram dissolves in 2.5 ml water. Sol in methanol, ethanol, chloroform. Practically insol in ether, benzene. Slightly acid to litmus. LD50 orally in rats: 225 mg/kg (Goldenthal).
Toxicity data: LD50 orally in rats: 225 mg/kg (Goldenthal)
 
Therap-Cat: Antiemetic; antipsychotic.
Therap-Cat-Vet: Antiemetic; tranquilizer.
Keywords: Antiemetic; Antipsychotic; Phenothiazines.