Home > Name List By other > (3S, 4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4- phenylpiperidine-4-carboxylic acid

CAS No 79516-68-0 , (3S,
4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-
phenylpiperidine-4-carboxylic acid

  • Name: (3S,
    4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-
    phenylpiperidine-4-carboxylic acid
  • Synonyms: Levocabastina; Levocabastinum [Latin];(3S,
    4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-
    phenylpiperidine-4-carboxylic acid; Levocabastinum; Levocabastin; Levocabastina [Spanish];Livostin; Levocabastine [INN:BAN];
  • CAS Registry Number:
  • Density: 1.23
  • Refractive index: 1.606
  • Molecular Weight: 420.519063
  • InchiKey: ZCGOMHNNNFPNMX-YHYDXASRSA-N
  • InChI: InChI=1S/C26H29FN2O2/c1-19-17-29(16-15-26(19,
    24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,
    14-12-23)20-7-9-22(27)10-8-20/h2-10,19,23H,11-17H2,1H3,(H,30,31)/t19-,
    23?,25?,26-/m1/s1
  • Molecular Formula: C26H29FN2O2
  • Molecular Structure:CAS No:79516-68-0 (3S,<br />4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-<br />phenylpiperidine-4-carboxylic acid
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79516-68-0 Levocabastin

  • Levocabastin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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79516-68-0 Levocabastine

  • Levocabastine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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79516-68-0 Levocabastine

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79516-68-0 LEVOCABASTINE

  • LEVOCABASTINE
  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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79516-68-0 LEVOCABASTINE

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79516-68-0 LEVOCABASTINE

  • LEVOCABASTINE
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
  • Fax: +91 79 30071176, 26574630
  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
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79516-68-0 4-Piperidinecarboxylicacid, 1-[cis-4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-, (3S,4R)-

  • China Shanghai Longsheng chemical Co.,Ltd [Manufacturers]
  • Tel: 86-21-35325969
  • Fax: 86-21-33191781
  • Address: No.3,Yuanjiang Road,Minhang District Shanghai,China Shanghai,ShanghaiChina
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79516-68-0 Levocabastin

  • Levocabastin
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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79516-68-0 LEVOCABASTIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of (3S,
4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-
phenylpiperidine-4-carboxylic acid
Title: Levocabastine
CAS Registry Number: 79516-68-0
CAS Name: [3S-[1(cis),3a,4b]]-1-[4-Cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid
Synonyms: (-)-trans-1-[cis-4-cyano-4-(p-fluorophenyl)cyclohexyl]-3-methyl-4-phenylisonipecotic acid; (-)-cabastine
Molecular Formula: C26H29FN2O2
Molecular Weight: 420.52
Percent Composition: C 74.26%, H 6.95%, F 4.52%, N 6.66%, O 7.61%
Literature References: Histamine H1-receptor antagonist. Prepn: R. Stokbroekx et al., EP 34415; eidem, US 4369184 (1981, 1983 both to Janssen); and pharmacology: R. A. Stokbroekx et al., Drug Dev. Res. 8, 87 (1986). Pharmacology: K. Tasaka et al., Arzneim.-Forsch. 40, 1295 (1990). Clinical pharmacology: N. Rombaut et al., Ann. Allergy 67, 75 (1991). Clinical trial in children with allergic conjunctivitis: M. Rimas et al., Allergy 45, 18 (1990); in allergic rhinitis: M. Schata et al., J. Allergy Clin. Immunol. 87, 873 (1991). Review of pharmacology and therapeutic use: K. L. Dechant, K. L. Goa, Drugs 41, 202-224 (1991).
 
Derivative Type: Hydrochloride
CAS Registry Number: 79547-78-7
Manufacturers' Codes: R-50547
Trademarks: Levophta (Chauvin); Livostin (Novartis)
Molecular Formula: C26H29FN2O2.HCl
Molecular Weight: 456.98
Percent Composition: C 68.34%, H 6.62%, F 4.16%, N 6.13%, O 7.00%, Cl 7.76%
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic.