Home > Name List By 2 > 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R...

CAS No 79-85-6 , 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R,4aS,5aS,6S,12aS)-

  • Name: 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R,4aS,5aS,6S,12aS)-
  • Synonyms: Quatrimycin (6CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R,4aS,5aS,6S,12aS)-;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,4-epimer (8CI); Epitetracycline; 4-Epitetracycline; 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4R-(4a,4ab,5ab,6a,12ab)]-;4-epi-Tetracycline; epi-Tetracycline;
  • CAS Registry Number:
  • Density: 1.64 g/cm3
  • Refractive index: 1.74
  • Molecular Weight: 444.4346
  • InChI: InChI=1/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,30-32H,7,23H2,1-3H3/b20-14-/t9-,10-,15+,21+,22-/m0/s1
  • Molecular Formula: C22H24 N2 O8
  • Molecular Structure:CAS No:79-85-6 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R,4aS,5aS,6S,12aS)-

Related products

Select to

79-85-6 4-Epitetracycline

  • 4-Epitetracycline
  • United States AvaChem Scientific LLC [Manufacturer]
  • Tel: 210-667-3815
  • Fax: 210-764-2240
  • Address: P.O.Box 78044278278 San Antonio, TexasUNITED STATES 78278 San Antonio, Texas,nullUnited States
Contact Supplier

79-85-6 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R,4aS,5aS,6S,12aS)-

  • United States AvaChem Scientific LLC [Manufacturers]
  • Tel: 210 667 3815
  • Address: P. O. Box 780442 San Antonio, TX 78278 U.S.A. null,nullUnited States
Contact Supplier

Select to

1/1
References of 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4R,4aS,5aS,6S,12aS)-
Title: Quatrimycin
CAS Registry Number: 79-85-6
CAS Name: [4R-(4a,4ab,5ab,6a,12ab)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
Synonyms: epitetracycline
Molecular Formula: C22H24N2O8
Molecular Weight: 444.43
Percent Composition: C 59.45%, H 5.44%, N 6.30%, O 28.80%
Literature References: Prepn by epimerization of tetracycline: McCormick et al., J. Am. Chem. Soc. 79, 2849 (1957); Kaplan et al., Antibiot. Chemother. 7, 569 (1957); Remmers et al., J. Pharm. Sci. 52, 752 (1963). Acute toxicity: L. Kung, H. Sun, Yao Hsueh Hsueh Pao 13, 244 (1966), C.A. 65, 7869e (1966).
 
Derivative Type: Monohydrate
Properties: Crystals, mp 178° dec. [a]D25 -335° (c = 0.5 in 0.03N HCl). uv max (0.01N H2SO4): 216, 255, 270, 355 (e 13,900, 16,400, 15,200, 14,700). LD50 i.v. in mice: 85.8 mg/kg (Kung, Sun).
Melting point: mp 178° dec
Optical Rotation: [a]D25 -335° (c = 0.5 in 0.03N HCl)
Absorption maximum: uv max (0.01N H2SO4): 216, 255, 270, 355 (e 13,900, 16,400, 15,200, 14,700)
Toxicity data: LD50 i.v. in mice: 85.8 mg/kg (Kung, Sun)
 
Derivative Type: Ammonium salt monohydrate
Molecular Formula: C22H27N3O8.H2O
Molecular Weight: 479.48
Percent Composition: C 55.11%, H 6.10%, N 8.76%, O 30.03%
Properties: Yellow crystals, mp 170° dec. [a]D25 -321° (c = 0.5 in 0.03N HCl). Soly in water >50 mg/kg.
Melting point: mp 170° dec
Optical Rotation: [a]D25 -321° (c = 0.5 in 0.03N HCl)
 
Derivative Type: Hydrochloride
Molecular Formula: C22H25ClN2O8
Molecular Weight: 480.90
Percent Composition: C 54.95%, H 5.24%, Cl 7.37%, N 5.83%, O 26.62%
Properties: Amorphous yellow solid. [a]D25 -325° (c = 0.58 in 0.2N HCl). Soly in water >100 mg/ml.
Optical Rotation: [a]D25 -325° (c = 0.58 in 0.2N HCl)
 
Derivative Type: Methiodide
Molecular Formula: C23H27IN2O8
Molecular Weight: 586.37
Percent Composition: C 47.11%, H 4.64%, I 21.64%, N 4.78%, O 21.83%
Properties: Crystals, mp 161-162°. [a]D25 -265° (c = 0.5 in 0.03N HCl).
Melting point: mp 161-162°
Optical Rotation: [a]D25 -265° (c = 0.5 in 0.03N HCl)