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CAS No 78628-28-1 , [2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate

  • Name: [2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate
  • Synonyms: Aceroxatidine; Roxatidina [Spanish]; BRN 5829308; Pifatidine; 78628-28-1; Roxatidinum [Latin]; Roxatidina;[2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate; Roxatidinum;
  • CAS Registry Number:
  • Density: 1.13 g/cm3
  • Refractive index: 1.532
  • Water Solubility: soluble in DMSO, insoluble in water and ethanol.
  • Molecular Weight: 348.43662
  • InchiKey: SMTZFNFIKUPEJC-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H28N2O4/c1-16(22)25-15-19(23)20-9-6-12-24-18-8-5-7-17(13-18)
    14-21-10-3-2-4-11-21/h5,7-8,13H,2-4,6,9-12,14-15H2,1H3,(H,20,23)
  • Molecular Formula: C19H28N2O4
  • Molecular Structure:CAS No:78628-28-1 [2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate
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78628-28-1 Roxatidine Acetate

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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78628-28-1 ROXATIDINE ACETATE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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78628-28-1 ROXATIDINE ACETATE

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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78628-28-1 ROXATIDINE ACETATE

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
  • Fax: 86-571-81956190 88386326
  • Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China. Hangzhou,ZhejiangChina
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78628-28-1 ROXATIDINE ACETATE

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78628-28-1 Acetamide,2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-

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78628-28-1 Acetamide,2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-

  • Canada Molcan Corporation [Importer/Exporter]
  • Tel: 905-731-5537, 905-731-6592, 1-888-237-7579
  • Fax: +416-267-9144
  • Address: 70 East Beaver Creek Road #39 Richmond Hill, Toronto, Ontario, Canada L4B 3B2 Toronto,OntarioCanada
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78628-28-1 Roxatidine Acetate

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78628-28-1 Roxatidine Acetate

  • India Spansules Pharmatech Pvt. Ltd. null
  • Tel: +91-(40)-23061309, 23061982
  • Fax: +91-(40)-23061979
  • Address: Plot No.39,G-3,Srivenkateswara Towers, Bhagyanagar Colony, Opp.KPHB., Hyderabad, Andhra Pradesh 500 072, null,nullIndia
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78628-28-1 Acetamide,2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-

  • China Knowshine (Shanghai) Pharmachemicals Inc. [Manufacturers]
  • Tel: +86-(21)-51320697
  • Fax: +86-(21)-51320699
  • Address: 1043 Halei Road, Suite 306, Zhangjiang Hi-tech Park, Shanghai 201203, Shanghai,ShanghaiChina
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References of [2-oxo-2-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]ethyl] acetate
Title: Roxatidine Acetate
CAS Registry Number: 78628-28-1
CAS Name: 2-(Acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide
Synonyms: aceroxatidine
Molecular Formula: C19H28N2O4
Molecular Weight: 348.44
Percent Composition: C 65.49%, H 8.10%, N 8.04%, O 18.37%
Literature References: Histamine H2-receptor antagonist. Prepn and anti-ulcerative activity: K. Shibata et al., EP 24510; eidem, US 4293557 (both 1981 to Teikoku Hormone). Pharmacology in animals: M. Tarutani et al., Arzneim.-Forsch. 35, 703 (1985). Comparison with cimetidine of effect on gastric acid secretion and ulcer formation in animals: eidem, ibid. 844. Metabolism in humans: S. Honma et al., Oyo Yakuri 30, 555 (1985); C.A. 104, 61453n (1985).
Properties: mp 59-60°. LD50 orally in male mice: 1000 mg/kg (Shibata).
Melting point: mp 59-60°
Toxicity data: LD50 orally in male mice: 1000 mg/kg (Shibata)
 
Derivative Type: Hydrochloride
CAS Registry Number: 93793-83-0
Synonyms: Pifatidine
Manufacturers' Codes: HOE-760; TZU-0460
Trademarks: Altat (Teikoku Hormone); Gastralgin (De Angeli); Neo H2 (Boehringer, Ing.); Roxit (Aventis)
Molecular Formula: C19H28N2O4.HCl
Molecular Weight: 384.90
Percent Composition: C 59.29%, H 7.59%, N 7.28%, O 16.63%, Cl 9.21%
Properties: mp 145-146°.
Melting point: mp 145-146°
 
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Histamine H2-Receptor Antagonist.