Title: Hexythiazox
CAS Registry Number: 78587-05-0
CAS Name: (4
R,5
R)-
rel-5-(4-Chlorophenyl)-
N-cyclohexyl-4-methyl-2-oxo-3-thiazolidinecarboxamide
Synonyms: trans-4-methyl-5-(4-chlorophenyl)-3-cyclohexylcarbamoyl-2-thiazolidone; HTZ
Manufacturers' Codes: NA-73; DPX-Y5893-9
Trademarks: Nissorun (Nippon Soda); Acariflor (Sipcam); Cesar (AgrEvo); Savey (Gowan); Zeldox (Zeneca)
Molecular Formula: C17H21ClN2O2S
Molecular Weight: 352.88
Percent Composition: C 57.86%, H 6.00%, Cl 10.05%, N 7.94%, O 9.07%, S 9.09%
Literature References: Prepn: I. Iwataki
et al., DE 3037105;
eidem, US 4442116 (1981, 1984 to Nippon Soda). Miticidal activity: M. A. Hoy, Y.- L. Ouyang,
J. Econ. Entomol. 79, 1377 (1986); C. Welty
et al., ibid. 81, 586 (1988). Residue determn in crops: M. Tokieda
et al., J. Pestic. Sci. 12, 711 (1987),
C.A. 108, 162770b (1988). Brief description of physical properties, toxicity and efficacy: Nippon Soda Co., Ltd.,
Jpn. Pestic. Inf. 44, 21 (1984).
Properties: White odorless crystals, mp 105.5°. Vapor pressure at 20°: 2.54 ′ 10-8 mm Hg. Soly at 20° (g/100 ml): acetone 16, chloroform 137.9, methanol 2.06,
n-hexane 0.39, xylene 36.2, acetonitrile 2.86; water 0.5 ppm. LD50 in male, female mice, male, female rats (mg/kg): all >5000 orally; all >5000 dermally (Nippon Soda Co.).
Melting point: mp 105.5°
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): all >5000 orally; all >5000 dermally (Nippon Soda Co.)
Use: Acaricide.