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CAS No 77-19-0 , [1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester

  • Name: [1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester
  • Synonyms: [Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester (6CI,7CI,8CI); Bentylol;Dicycloverin; Wyovin; Bentyl; Diocyl; Dicycloverine;[1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester; Dicyclomine;
  • CAS Registry Number:
  • Melting Point: 309.487
  • EINECS: 201-009-4
  • Molecular Weight: 309.4867
  • InchiKey: CURUTKGFNZGFSE-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
  • Molecular Formula: C19H35NO2
  • Molecular Structure:CAS No:77-19-0 [1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester

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77-19-0 Dicycloverine

  • IUPAC NAME-2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate MOLECULAR FORMULA-C19H35NO2 MOLAR MASS-309.487 g/mol icycloverine, also known as dicyclomine, is an anticholinergic that blocks muscarinic receptors icyclomine is used to treat in...
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77-19-0 [1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester

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77-19-0 DICYCLOMINE

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References of [1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester
Title: Dicyclomine
CAS Registry Number: 77-19-0
CAS Name: [1,1￠-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester
Synonyms: b-diethylaminoethyl 1-cyclohexylcyclohexanecarboxylate; bis(cyclohexyl)carboxylic acid diethylaminoethyl ester; dicycloverin
Molecular Formula: C19H35NO2
Molecular Weight: 309.49
Percent Composition: C 73.74%, H 11.40%, N 4.53%, O 10.34%
Literature References: Anticholinergic; binds to muscarinic M1 receptors. Prepn: C. H. Tilford et al., J. Am. Chem. Soc. 69, 2903 (1947); M. G. Van Campen, C. H. Tilford, US 2474796 (1949 to Merrell). Receptor binding study: H. Kilbinger, A. Stein, Br. J. Pharmacol. 94, 1270 (1988). Capillary GC determn in plasma: B. J. Walker et al., J. Chromatogr. 416, 150 (1987). Clinical trial in functional abdominal pain: M. G. Grillage et al., Br. J. Clin. Pract. 44, 176 (1990).
 
Derivative Type: Hydrochloride
CAS Registry Number: 67-92-5
Trademarks: Bentyl (Aventis); Bentylol (Aventis); Merbentyl (Aventis); Wyovin (Wyeth)
Molecular Formula: C19H35NO2.HCl
Molecular Weight: 345.95
Percent Composition: C 65.96%, H 10.49%, N 4.05%, O 9.25%, Cl 10.25%
Properties: Crystals from butanone, mp 164-166°. Bitter taste. Sol in water; freely sol in alcohol, chloroform; very slightly sol in ether.
Melting point: mp 164-166°
 
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.