Title: Alloxantin
CAS Registry Number: 76-24-4
CAS Name: 5,5¢-Dihydroxy-[5,5¢-bipyrimidine]-2,2¢,4,4¢,6,6¢(1
H,1¢
H,3
H,3¢
H,5
H,5¢
H)-hexone
Synonyms: 5,5¢-dihydroxy-5,5¢-bibarbituric acid; uroxin
Molecular Formula: C8H6N4O8
Molecular Weight: 286.16
Percent Composition: C 33.58%, H 2.11%, N 19.58%, O 44.73%
Literature References: Prepd from uric acid: Nightingale,
Org. Synth. coll. vol. III, 42 (1955); from alloxan monohydrate: Tipson,
ibid. coll. vol. IV, 25 (1963). Structure: Singh,
Acta Crystallogr. 19, 767 (1965).
Derivative Type: Dihydrate
Properties: Cryst powder. On exposure to air becomes red. Becomes yellow at 225°; dec at 253-255°. Sparingly sol in cold water, alcohol or ether. Its aq soln is acid; reduces Ag salts and gives a blue ppt with Ba(OH)2 soln.
Keep tightly closed. Emits toxic fumes upon decompn.
CAUTION: Ingestion causes disturbed carbohydrate metabolism leading to diabetes,
cf. Dangerous Properties of Industrial Materials, N. I. Sax, Ed. (Van Nostrand Reinhold, New York, 4th ed., 1975) p 366.