Home > Name List By 4 > 4-chloro-N-(4, 5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine

CAS No 75438-57-2 , 4-chloro-N-(4,
5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine

  • Name: 4-chloro-N-(4,
    5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
  • Synonyms: Lomox; Cynt;Norcynt; Normoxocin; BE 5895; Physiotens; 75438-57-2; Moxonidinum [Latin]; Nucynt;4-chloro-N-(4,
    5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine;
  • CAS Registry Number:
  • Flash Point: 174.3°C
  • Boiling Point: 364.7°C at 760 mmHg
  • Density: 1.52 g/cm3 (20 C)
  • Refractive index: 1.68
  • Flash Point: 174.3°C
  • Molecular Weight: 241.67748
  • InchiKey: WPNJAUFVNXKLIM-UHFFFAOYSA-N
  • InChI: InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,
    1-2H3,(H2,11,12,15)
  • Molecular Formula: C9H12ClN5O
  • Molecular Structure:CAS No:75438-57-2 4-chloro-N-(4,<br />5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine

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References of 4-chloro-N-(4,
5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
Title: Moxonidine
CAS Registry Number: 75438-57-2
CAS Name: 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
Synonyms: 4-chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-yl)aminopyrimidine
Manufacturers' Codes: BDF-5895
Trademarks: Cynt (Beiersdorf); Physiotens (Giulini)
Molecular Formula: C9H12ClN5O
Molecular Weight: 241.68
Percent Composition: C 44.73%, H 5.00%, Cl 14.67%, N 28.98%, O 6.62%
Literature References: a2-Adrenoceptor agonist. Prepn: NL 7908192; W. Stenzel et al., US 4323570 (1980, 1982 both to Beiersdorf AG). Series of articles on pharmacology and binding studies: Arzneim.-Forsch. 38, 1426-1445 (1988). Pharmacokinetics: D. Trenk et al., J. Clin. Pharmacol. 27, 988 (1987); W. Kirch et al., ibid. 30, 1088 (1990). Clinical comparison with clonidine, q.v.: V. Pl?nitz, ibid. 27, 46 (1987).
Properties: mp 217-219° (dec).
Melting point: mp 217-219° (dec)
 
Derivative Type: Hydrochloride
CAS Registry Number: 75438-58-3
Properties: Crystals from isopropanol/ether, mp 189°.
Melting point: mp 189°
 
Therap-Cat: Antihypertensive.
Keywords: a-Adrenergic Agonist; Antihypertensive; Imidazole Derivatives.