Title: Tribromoethanol
CAS Registry Number: 75-80-9
Synonyms: Tribromoethyl alcohol
Molecular Formula: C2H3Br3O
Molecular Weight: 282.76
Percent Composition: C 8.50%, H 1.07%, Br 84.78%, O 5.66%
Line Formula: Br3CCH2OH
Literature References: Prepd by the reduction of bromal with aluminum isopropylate:
US 1572742 (1926);
US 1725054 (1929);
US 1882944 (1932). Acute toxicity: R. R. Burtner, G. Lehmann,
J. Pharmacol. Exp. Ther. 63, 183 (1938).
Properties: Crystals, mp 79-82°, decompn starting at 70°. bp10 92-93°. Slight ethereal or aromatic odor and taste. Sol in 40 parts water at 40°; sol in alcohol, ether, benzene, warm petr ether; very sol in amylene hydrate. The aq and alcoholic solns dec on exposure to light; in aq soln dibromoacetaldehyde and HBr are formed, both of which are strongly irritant.
Protect from light. LD50 orally in rats: 1.09 g/kg (Burtner, Lehmann).
Melting point: mp 79-82°
Boiling point: bp10 92-93°
Toxicity data: LD50 orally in rats: 1.09 g/kg (Burtner, Lehmann)
Derivative Type: Solution in amylene hydrate
Synonyms: Bromethol
Trademarks: Avertin (Winthrop)
Therap-Cat: Has been used as a basal anesthetic.
Therap-Cat-Vet: Has been used as a general anesthetic and narcotic.
Status: This monograph has been retired and is no longer subject to revision or update.