Home > Name List By 2 > 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]a...

CAS No 74863-84-6 , 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-

  • Name: 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-
  • Synonyms: 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-; Acova; Argipidin; DK 7419; Argatroban; MD 805; OM 805; Novastan; Slonnon; MCI 9038; GN 1600;Argipidine; Argatra; MQPA;2-Piperidinecarboxylicacid,1-[5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,[2R-[1(2S*),2a,4b]]-[partial]-;
  • CAS Registry Number:
  • Melting Point: 188-1890C
  • Density: 1.47 g/cm3
  • Molecular Weight: 508.63
  • InChI: InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15?,17+,18-/m1/s1
  • Molecular Formula: C23H36 N6 O5 S
  • Molecular Structure:CAS No:74863-84-6 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-
Search by region :

Select to

74863-84-6 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
Contact Supplier

74863-84-6 Argatroban

  • ArgatrobanArgatroban, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,China
Contact Supplier

74863-84-6 Argatroban

  • Argatroban, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,China
Contact Supplier

74863-84-6 Argatroban

  • Argatroban
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
Contact Supplier

74863-84-6 Argatroban

  • Argatroban, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
Contact Supplier

74863-84-6 Argatroban

  • Argatroban
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
  • Fax: 19735811283
  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,United States
Contact Supplier

74863-84-6 Argatroban

  • Argatroban, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
Contact Supplier

74863-84-6 Argatroban

  • Argatroban, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
Contact Supplier

74863-84-6; 141396-28-3 Argatroban

Contact Supplier

74863-84-6 Argatroban

Contact Supplier

Select to

References of 2-Piperidinecarboxylicacid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-
Title: Argatroban
CAS Registry Number: 74863-84-6
CAS Name: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid
Synonyms: (2R,4R)-4-methyl-1-[N2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-2-piperidinecarboxylic acid; (2R,4R)-4-methyl-1-[(S)-N2-[[(R,S)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl]sulfonyl]arginyl]pipecolic acid; argipidine; MQPA
Molecular Formula: C23H36N6O5S
Molecular Weight: 508.63
Percent Composition: C 54.31%, H 7.13%, N 16.52%, O 15.73%, S 6.30%
Literature References: Synthetic thrombin inhibitor. Prepn of argatroban and stereoisomers: R. Kikumoto et al., EP 8746; S. Okamoto et al., US 4258192 (1980, 1981 both to Mitsubishi Chem. Ind.); S. Okamoto et al., Biochem. Biophys. Res. Commun. 101, 440 (1981). Comparison with heparin, q.v., of antithrombotic effect in animals: T. Kumada, Y. Abiko, Thromb. Res. 24, 285 (1981). Stereoselective inhibition of thrombin: R. Kikumoto et al., Biochemistry 23, 85 (1984). Clinical evaluation in hemodialysis: K. Ota et al., Proc. Eur. Dial. Transplant. Assoc. 20, 144 (1983); in disseminated intravascular coagulation: K. Kumon et al., Crit. Care Med. 12, 1039 (1984).
Properties: Crystals from ethanol, mp 188-191°.
Melting point: mp 188-191°
 
Derivative Type: Monohydrate
CAS Registry Number: 141396-28-3
Manufacturers' Codes: DK-7419; MCI-9038; MD-805; OM-805
Trademarks: Novastan (Tokyo Tanabe); Slonnon (Daiichi)
Properties: Crystals from aq ethanol, mp 176-180°. [a]D27 +76.1° (c = 1 in 0.2N HCl).
Melting point: mp 176-180°
Optical Rotation: [a]D27 +76.1° (c = 1 in 0.2N HCl)
 
Therap-Cat: Antithrombotic.
Keywords: Antithrombotic.