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CAS No 73-49-4 , 7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide

  • Name: 7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide
  • Synonyms: Quinetazona [INN-Spanish]; Quinethazonum;Chinethazonum; Chinetazone [DCIT]; Aquamox; Hydromox; Quinethazon; Idrokin;7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide;
  • CAS Registry Number:
  • Melting Point: 250 - 252 C
  • Density: 1.425g/cm3
  • Refractive index: 1.582
  • Water Solubility: negligible
  • EINECS: 200-801-7
  • Molecular Weight: 289.73858
  • InchiKey: AGMMTXLNIQSRCG-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,
    16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17)
  • Molecular Formula: C10H12ClN3O3S
  • Molecular Structure:CAS No:73-49-4 7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide

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References of 7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide
Title: Quinethazone
CAS Registry Number: 73-49-4
CAS Name: 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamide
Synonyms: 7-chloro-2-ethyl-6-sulfamoyl-1,2,3,4-tetrahydro-4-quinazolinone; 7-chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-sulfamoylquinazoline
Manufacturers' Codes: CL-36010
Trademarks: Hydromox (Lederle); Aquamox (Lederle)
Molecular Formula: C10H12ClN3O3S
Molecular Weight: 289.74
Percent Composition: C 41.45%, H 4.17%, Cl 12.24%, N 14.50%, O 16.57%, S 11.07%
Literature References: Prepn: Cohen et al., J. Am. Chem. Soc. 82, 2731 (1960); Cohen, Vaughan, Jr., US 2976289 (1961 to Am. Cyanamid).
Properties: Fibrous crystals from 50% acetone, mp 250-252°. Sol in acetone, alcohol.
Melting point: mp 250-252°
Therap-Cat: Diuretic, antihypertensive.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.