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CAS No 2127-01-7 , 6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide

  • Name: 6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide
  • Synonyms: Clorexolona [INN-Spanish]; Nefrolan; Clorexolon; Klorex;6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide; Flonatril; 2127-01-7;Chlorexolone; Cloresolone [DCIT]; Clorexolonum [INN-Latin];
  • CAS Registry Number:
  • Flash Point: 302.9°C
  • Boiling Point: 577.2°Cat760mmHg
  • Density: 1.447g/cm3
  • Refractive index: 1.631
  • Flash Point: 302.9°C
  • EINECS: 218-342-6
  • Molecular Weight: 328.81438
  • InchiKey: VPMWFZKOWULPGT-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H17ClN2O3S/c15-12-6-9-8-17(10-4-2-1-3-5-10)14(18)11(9)7-13
    (12)21(16,19)20/h6-7,10H,1-5,8H2,(H2,16,19,20)
  • Molecular Formula: C14H17ClN2O3S
  • Molecular Structure:CAS No:2127-01-7 6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide

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References of 6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide
Title: Clorexolone
CAS Registry Number: 2127-01-7
CAS Name: 6-Chloro-2-cyclohexyl-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonamide
Synonyms: 6-chloro-2-cyclohexyl-3-oxo-5-isoindolinesulfonamide; 5-chloro-2-cyclohexyl-1-oxo-6-sulfamoylisoindoline; 5-chloro-2-cyclohexyl-6-sulfamoylisoindolin-1-one; 5-chloro-2-cyclohexylphthalimidine-6-sulfonamide
Manufacturers' Codes: M & B 8430; RP-12833
Trademarks: Flonatril (Specia); Nefrolan (M & B)
Molecular Formula: C14H17ClN2O3S
Molecular Weight: 328.81
Percent Composition: C 51.14%, H 5.21%, Cl 10.78%, N 8.52%, O 14.60%, S 9.75%
Literature References: Prepn: BE 620654; G. E. Lee, W. R. Wragg, US 3183243 (1963, 1965 both to May & Baker).
Properties: Prisms, mp 266-268°. Soly in water at 25°: 16 mg/l.
Melting point: mp 266-268°
Therap-Cat: Diuretic.
Keywords: Diuretic; Sulfonamide Derivatives.