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CAS No 72432-03-2 , (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

  • Name: (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
  • Synonyms: Glyset; Seibule; Glyset (TN); Diastabol; Bay-m-1099; 72432-03-2; Plumarol;(2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol; CHEMBL1561; AC1L9AYD;
  • CAS Registry Number:
  • Melting Point: 114 ºC
  • Density: 1.458 g/cm3
  • Refractive index: 1.597
  • EINECS: 276-661-6
  • Molecular Weight: 207.22428
  • InchiKey: IBAQFPQHRJAVAV-ULAWRXDQSA-N
  • InChI: InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,
    1-4H2/t5-,6+,7-,8-/m1/s1
  • Molecular Formula: C8H17NO5
  • Molecular Structure:CAS No:72432-03-2 (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

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72432-03-2 Miglitol

  • IUPAC NAME-(2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl) piperidine-3,4,5-triol MOLECULAR FORMULA-C8H17NO5 MOLAR MASS-207.224 g/mol
  • India Swapnroop Drugs and Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia
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72432-03-2 Miglitol

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72432-03-2 Miglitol

  • China Shanghai Fchemicals Technology Co., Ltd. [Manufacturers]
  • Tel: +86-(21)-36030322
  • Fax: +86-(21)-66315383
  • Address: Room524,Hua-Rui Mansion No.18 Jiang Chang Yi Road, Shanghai 200436, Shanghai,ShanghaiChina
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72432-03-2 MIGLITOL

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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72432-03-2 Miglitol

  • China SHANGHAI HANHONG CHEMICAL,CO.,LTD. [Manufacturers]
  • Tel: +86-18917911573
  • Fax: +21 54291107
  • Address: Room 207,Zenghe Building ,Jiachuan Road 245, Xuhui District, Shanghai, China shang hai,shang haiChina
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72432-03-2 Miglitol

  • China HuaiBei SanHe Developing Co., Ltd. [Manufacturers]
  • Tel: 86-561-3191113
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  • Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China null,anhuiChina
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72432-03-2 MIGLITOL

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
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References of (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Title: Miglitol
CAS Registry Number: 72432-03-2
CAS Name: 1,5-Dideoxy-1,5-[(2-hydroxyethyl)imino]-D-glucitol
Synonyms: N-(2-hydroxyethyl)moranoline; (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol; N-(b-hydroxyethyl)-1-deoxynojirimycin
Manufacturers' Codes: Bay m 1099
Trademarks: Diastabol (Sanofi-Synthelabo); Glyset (Pfizer)
Molecular Formula: C8H17NO5
Molecular Weight: 207.22
Percent Composition: C 46.37%, H 8.27%, N 6.76%, O 38.60%
Literature References: a-Glucosidase inhibitor; hydroxyethyl derivative of 1-deoxynojirimycin, q.v. Prepn: B. Junge et al., DE 2758025; eidem, US 4639436 (1979, 1987 both to Bayer AG). Inhibition of a-glucosidase: B. Lembcke et al., Digestion 31, 120 (1985); and hypoglycemic activity: Y. Yoshikuni et al., J. Pharmacobio-Dyn. 11, 356 (1988). Clinical evaluations in insulin dependent diabetes: J. Gerard et al., Int. J. Clin. Pharmacol. Ther. Toxicol. 25, 483 (1987); F. P. Kennedy, J. E. Gerich, Clin. Pharmacol. Ther. 42, 455 (1987). Review of pharmacology, clinical efficacy, and therapeutic potential in non-insulin dependent diabetes: L. J. Scott, C. M. Spencer, Drugs 59, 521-549 (2000).
Properties: Crystals from ethanol, mp 114°. Sol in water. pKa 5.9.
Melting point: mp 114°
pKa: pKa 5.9
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; a-Glucosidase Inhibitor.