Home > Name List By other > (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-ol

CAS No 72-33-3 , (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,
16-octahydro-6H-cyclopenta[a]phenanthren-17-ol

  • Name: (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,
    16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
  • Synonyms: Compound 33355; EE(sub3)ME; Menophase; Mestranolum; 72-33-3;Devocin;(8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,
    16-octahydro-6H-cyclopenta[a]phenanthren-17-ol; Ovastol; Ethynylestradiol 3-methyl ether; Norquen;
  • CAS Registry Number:
  • Melting Point: 150-154 ºC
  • Density: 0.905g/cm3
  • Refractive index: 1.49
  • Safety Statements: Confirmed carcinogen with experimental neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by subcutaneous route. Human reproductive effects by ingestion: changes in ovaries and fallopian tubes, fertility effects. Experimental reproductive effects. Mutation data reported. An FDA proprietary drug. A steroid used in oral contraceptives. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-777-8
  • Molecular Weight: 310.42994
  • InchiKey: IMSSROKUHAOUJS-MJCUULBUSA-N
  • InChI: InChI=1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17
    (18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,
    20+,21+/m1/s1
  • Risk Statements: R36/37/38;R40;R48
  • Molecular Formula: C21H26O2
  • Molecular Structure:CAS No:72-33-3 (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,<br />16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
Search by region :

Select to

72-33-3 Mestranol

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
  • Fax: 86-571-81956190 88386326
  • Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China. Hangzhou,ZhejiangChina
Contact Supplier

72-33-3 Mestranol

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
Contact Supplier

72-33-3 Mestranol

Contact Supplier

72-33-3 MESTRANOL

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
Contact Supplier

72-33-3 MESTRANOL

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

72-33-3 MESTRANOL

  • China Taizhou Creating Chemical Co.,Ltd [Manufacturer]
  • Tel: +86-576-88827176/ +86-576-88820069
  • Fax: +86-576-88822496
  • Address: B Suite 12F,
    Jiangbin Building,Jiaojiang,Taizhou,
    Zhejiang China null,nullChina
Contact Supplier

72-33-3 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol,3-methoxy-, (17a)-

Contact Supplier

72-33-3 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol,3-methoxy-, (17a)-

Contact Supplier

72-33-3 MESTRANOL

  • China Beijing Zizhu Pharmaceutical Co.,Ltd [Manufacturer]
  • Tel: +86-10-62250847/ +86-10-62250847
  • Fax: +86-10-62250810
  • Address: Beijing Zizhu Pharmaceutical Co., LTD, International Trade Department
    No.44 Honglian Nancun, Haidian District, Beijing, 100082 null,nullChina
Contact Supplier

Select to

References of (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,
16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
Title: Mestranol
CAS Registry Number: 72-33-3
CAS Name: (17a)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol
Synonyms: 17a-ethynyl-3-methoxy-1,3,5(10)-estratrien-17b-ol; 17a-ethynylestradiol 3-methyl ether
Trademarks: Menophase (Syntex); Norquen (Syntex); Ovastol
Molecular Formula: C21H26O2
Molecular Weight: 310.43
Percent Composition: C 81.25%, H 8.44%, O 10.31%
Literature References: Orally active estrogenic steroid. Prepn: F. B. Colton, US 2666769 (1954 to Searle); J. Am. Chem. Soc. 79, 1123 (1957). Comprehensive description: H. A. El-Obeid, A. A. Al-Badr, Anal. Profiles Drug Subs. 11, 375-406 (1982). Clinical pharmacokinetics: J. W. Goldzieher et al., Contraception 21, 17 (1980). Effect on carbohydrate metabolism: W. N. Spellacy et al., Metabolism 31, 106 (1982). Randomized, double-blind clinical trials: S. Koetsawang et al., Contraception 25, 231 (1982); A. Sheth et al., ibid. 243. Evaluation of carcinogenic risk: IARC Monographs 21, 257 (1979).
Properties: Crystals from methanol or acetone, mp 150-151°. uv max (methanol): 279, 287.5 nm (E1%1cm 82, 14.4). Sol in ethanol, ether, chloroform, dioxane, acetone. Slightly sol in methanol. Practically insol in water.
Melting point: mp 150-151°
Absorption maximum: uv max (methanol): 279, 287.5 nm (E1%1cm 82, 14.4)
NOTE: Also used in combination with chlormadinone acetate, ethynodiol, lynestrenol, norethindrone or norethynodrel, q.q.v. Has been used in combination with megestrol acetate, q.v.
CAUTION: This substance is listed as a known human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-115.
Therap-Cat: Estrogen; in combination with progestogen as oral contraceptive.
Keywords: Contraceptive (Oral); Estrogen; Steroidal.