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CAS No 69975-86-6 , 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione

  • Name: 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione
  • Synonyms: Ansimar;7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione; ABC 12/3;Doxophylline; Ventax; Doxofilina [INN-Spanish]; Dioxyfilline; Maxivent; 69975-86-6;
  • CAS Registry Number:
  • Melting Point: 144-146 ºC
  • Flash Point: 505.2 ºC at 760 mmHg
  • Boiling Point: 505.2 ºC at 760 mmHg
  • Density: 1.59 g/cm3
  • Refractive index: 1.7
  • Safety Statements: S26;S36/37;
  • Hazard Symbols: Xi
  • Flash Point: 505.2 ºC at 760 mmHg
  • EINECS: 274-239-6
  • Molecular Weight: 266.25326
  • InchiKey: HWXIGFIVGWUZAO-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-
    19-7/h6-7H,3-5H2,1-2H3
  • Risk Statements: 36/37/38
  • Molecular Formula: C11H14N4O4
  • Molecular Structure:CAS No:69975-86-6 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione
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69975-86-6 DOXOFYLLINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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69975-86-6 Doxofylline

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69975-86-6 doxophylline

  • IUPAC NAME-7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione MOLECULAR FORMULA-C11H14N4O4 MOLAR MASS-266.25 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

69975-86-6 Doxofylline

  • Doxofylline Product Name Doxofylline English Name Doxofylline CAS RN 69975-86-6 Chemical Name 1H-purine-2,6-dione, 7-(1,3-dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-; 274-239-6; 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-di...
  • Min. Order: 1000
  • FOB Price: USDfalse - false /
  • China Hubei Widely Chemical Technology Co., Ltd [Manufacturer, Trading Company]
  • Tel: 86-027-59402396
  • Address: 204#,Jiefang Avenue,Qiaokou District,Wuhan wuhan,HebeiChina
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69975-86-6 Doxofylline

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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69975-86-6 Doxofylline

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69975-86-6 Doxofylline

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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69975-86-6 Doxofylline

  • China Ningbo Inno Pharmchem Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-87319282
  • Fax: +86-(574)-56877908
  • Address: 5F, Building 4, 1035 Guangxian Rd., Ningbo Hi-Tech Park, Ningbo, Zhejiang 315040, Ningbo,ZhejiangChina
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69975-86-6 Doxofylline

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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69975-86-6 Doxofylline

  • China Goly Chemical Co., Ltd. [Manufacturers]
  • Tel: +86-(632)-6163187
  • Fax: +86-(632)-5100028
  • Address: Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102, ZaoZhuang,ShanDongChina
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References of 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione
Title: Doxofylline
CAS Registry Number: 69975-86-6
CAS Name: 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Synonyms: 7-(1,3-dioxolan-2-ylmethyl)theophylline; 2-(7¢-theophyllinemethyl)-1,3-dioxolane; doxophylline; dioxyfilline
Manufacturers' Codes: ABC-12/3
Trademarks: Ansimar (ABC); Maxivent; Ventax (Robert)
Molecular Formula: C11H14N4O4
Molecular Weight: 266.25
Percent Composition: C 49.62%, H 5.30%, N 21.04%, O 24.04%
Literature References: Prepn: U. Avico et al., Farmaco Ed. Sci. 17, 73 (1962). Use as bronchodilator: BE 868556; J. S. Franzone, T. Tamietto, US 4187308 (1978, 1980 to Istituto Biologico Chemioterapico ABC). Pharmacology: J. S. Franzone et al., Farmaco Ed. Sci. 36, 201 (1981). Pharmacodynamics and toxicity in rats: J. S. Franzone et al., ibid. 220. HPLC determn in pharmaceutical compositions: C. Badini et al., Farmaco Ed. Prat. 37, 320 (1982). Clinical trial in obstructive pneumopathy: C. Bucca et al., Int. J. Clin. Pharmacol. Res. 11, Suppl 1, 101 (1982).
Properties: Crystals, mp 144-145.5°. Sol in water, acetone, ethyl acetate, benzene, chloroform, dioxane, hot methanol or hot ethanol. Practically insol in ethyl ether or petr ether. LD50 in mice (mg/kg): 841 orally; 215.6 i.v.; in rats: 1022.4 orally, 445 i.p. (Franzone).
Melting point: mp 144-145.5°
Toxicity data: LD50 in mice (mg/kg): 841 orally; 215.6 i.v.; in rats: 1022.4 orally, 445 i.p. (Franzone)
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Xanthine Derivatives.