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CAS No 69-65-8 , (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

  • Name: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
  • Synonyms: mannitol; Osmosal; Resectisol; Diosmol;(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol; Osmofundin; Osmitrol; Invenex;D-mannitol; Marine Crystal; Mannite;
  • CAS Registry Number:
  • Melting Point: 167-170 ºC
  • Boiling Point: 295 ºC
  • Density: 1.52
  • Refractive index: 1.333 (20 C)
  • Alpha: 141 º (C= USP-DIRECTIVES)
  • Safety Statements: Mildly toxic by ingestion, intraperitoneal, and intravenous routes. Human systemic effects by intravenous route: blood pressure elevation, bladder tubule changes, nausea or vomiting. Human mutation data reported. Used as a nutrient and/or dietary supplement food additive. When heated to decomposition it emits acrid smoke and fumes.
  • Hazard Symbols: Xi
  • HS Code: 29054300
  • EINECS: 200-711-8
  • Molecular Weight: 182.17176
  • InchiKey: FBPFZTCFMRRESA-KVTDHHQDSA-N
  • InChI: InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,
    6-/m1/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H14O6
  • Molecular Structure:CAS No:69-65-8 (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
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87-78-5; 69-65-8 MANNITOL

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69-65-8 D-MANNITOL

  • United States ProChem, Inc. [Manufacturer]
  • Tel: 800-795-8788
  • Address: ProChem, Inc.
    826 Roosevelt Rd.
    Rockford IL 61109 null,nullUnited States
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69-65-8 MANNITOL

  • United States Seidler Chemical Company [Manufacturer]
  • Tel: (973) 465-1122
  • Fax: (973) 465-4469
  • Address: 537 Raymond Blvd.
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69-65-8 D-Mannitol

  • China Hubei Prosperity Galaxy Chemical Co.,Ltd. [Distributor/Wholesaler]
  • Tel: 027-83555670
  • Fax: 027-83557790
  • Address: No.25, Zhenxing Road, Jianghan District, Wuhan City, Hubei Province, China wuhan,hbxyh001@gmail.comChina
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69-65-8 D-MANNITOL

  • United States Fisher Scientific Company [Manufacturer]
  • Tel: 1-800-766-7000
  • Address: Fisher Scientific Company
    2000 Park Lane
    Pittsburgh, PA 15275 null,nullUnited States
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69-65-8 MANNITOL

  • United States Wintersun Chemical [Manufacturer]
  • Tel: 800-930-1688
  • Fax: 909-947-1788
  • Address: Wintersun Chemical
    3100 East Cedar Street, Suite 15
    Ontario, CA 91761 USA null,nullUnited States
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87-78-5; 69-65-8 MANNITOL

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87-78-5; 69-65-8 MANNITOL

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69-65-8 D-Mannitol

  • China Nanjing Chemical Reagent Co., Ltd. [Manufacturers]
  • Tel: +86-(25)-8532-3169, 8532-3128, 8532-1262
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  • Address: NO.18,YanyaoRoad, Nanjing, Jiangsu 210038, Nanjing,JiangsuChina
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87-78-5; 69-65-8 Mannitol

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References of (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
Title: Mannitol
CAS Registry Number: 69-65-8
Synonyms: D-Mannitol; mannite; manna sugar; cordycepic acid
Trademarks: Manicol; Mannidex; Osmitrol (Baxter); Osmosal; Resectisol (McGaw)
Molecular Formula: C6H14O6
Molecular Weight: 182.17
Percent Composition: C 39.56%, H 7.75%, O 52.70%
Literature References: Widespread in plants and plant exudates; obtained from manna and seaweeds: The Carbohydrates, W. Pigman, Ed. (Academic Press, New York, 1957) pp 249-250. Forms a stable, equimolar compound with H2O2: S. Tanatar, J. Russ. Phys. Chem. Soc. 40, 376, C.A. 3, 883 (1909). Prepd by electrolytic reduction of glucose: Creighton, Can. Chem. Process Ind. 26, 690 (1942), C.A. 37, 10885 (1943); Wolfrom et al., J. Am. Chem. Soc. 68, 578 (1946). Prepn from seaweed: Sorensen, Kristensen, US 2516350 (1950); by hydrogenation of invert sugar, monosaccharides, and sucrose: Kasehagen, and Kasehagen, Luskin, US 2642462, US 2749371, and US 2759024 (1953, 1956, and 1956, all to Atlas Powder). Review of prepn: Pigman, loc. cit. Novel synthesis: M. Makkee et al., Chem. Commun. 1980, 930.
Properties: Orthorhombic needles from alc, mp 166-168°. Sweetish taste. d20 1.52. bp3.5 290-295°. Is inactive or very slightly levorotatory in distilled water. Forms sodium mannitoborate on addition of borax giving a greater rotation: [a]D20 +23° ? +24° after 1 hr in a soln of 10 g mannitol +12.8 g borax + sufficient H2O to make 100 ml. One gram dissolves in ~5.5 ml water, 83 ml alcohol; more sol in hot water. Insol in ether. Sol in pyridine, aniline, aq solns of alkalies. One gram dissolves in 18 ml glycerol (d 1.24). Soly tables: Creighton, Klauder, J. Franklin Inst. 195, 687 (1923). pKa (18°): 13.50.
Melting point: mp 166-168°
Boiling point: bp3.5 290-295°
pKa: pKa (18°): 13.50
Optical Rotation: [a]D20 +23° ? +24° after 1 hr in a soln of 10 g mannitol +12.8 g borax + sufficient H2O to make 100 ml
Density: d20 1.52; d 1.24
Use: Used with boric acid in the manuf of dry electrolytic condensers for radio applications; in making artificial resins and plasticizers; in pharmacy as excipient and diluent for solids and liqs; in analytical chemistry for boron determinations; in the manuf of mannitol hexanitrate. Used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
Therap-Cat: Diuretic. Diagnostic aid (renal function).
Keywords: Diagnostic Aid; Diuretic.