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CAS No 69-27-2 , trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,
3-dihydroisoindol-2-ium-2-yl)ethyl]azanium

  • Name: trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,
    3-dihydroisoindol-2-ium-2-yl)ethyl]azanium
  • Synonyms: Chlorisondamine chloride;trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,
    3-dihydroisoindol-2-ium-2-yl)ethyl]azanium; Chlorisondamine dimethochloride; Ecolid; Ecolid chloride; Ecolid R; Hisindamone A;dichloride;
  • CAS Registry Number:
  • Safety Statements: Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of Cl−, NH3 and NOx.
  • Hazard Symbols: Xn,N
  • Molecular Weight: 429.04
  • InchiKey: DXXUGBPKQDTBQW-UHFFFAOYSA-L
  • InChI: InChI=1S/C14H20Cl4N2.2ClH/c1-19(2,
    3)5-6-20(4)7-9-10(8-20)12(16)14(18)13(17)11(9)15;;/h5-8H2,
    1-4H3;2*1H/q+2;;/p-2
  • Risk Statements: 22-50
  • Molecular Formula: C14H20Cl6N2
  • Molecular Structure:CAS No:69-27-2 trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,<br />3-dihydroisoindol-2-ium-2-yl)ethyl]azanium

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69-27-2 Chlorisondamine Diiodide

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69-27-2 4,5,6,7-Tetrachloro-1,3-dihydro-2-methyl-2-[2-trimethylammonium)ethyl]-2H-isoindolium diiodide

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69-27-2 1001 CHLORISONDAMINE DIIODIDE

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69-27-2 Chlorisondamine diiodide

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1/1
References of trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,
3-dihydroisoindol-2-ium-2-yl)ethyl]azanium
Title: Chlorisondamine Chloride
CAS Registry Number: 69-27-2
CAS Name: 4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-2H-isoindolium dichloride
Synonyms: 4,5,6,7-tetrachloro-2-(2-dimethylaminoethyl)-2-methylisoindolinium chloride methochloride; 4,5,6,7-tetrachloro-2-(2-dimethylaminoethyl)isoindoline dimethylchloride; N-[(2-dimethylammonium)ethyl]-4,5,6,7-tetrachloroisoindolinium dimethochloride; chlorisondamine dimethochloride; Ecolid
Molecular Formula: C14H20Cl6N2
Molecular Weight: 429.04
Percent Composition: C 39.19%, H 4.70%, Cl 49.58%, N 6.53%
Literature References: Nicotinic receptor antagonist of the ganglion blocking class. Prepn: Allen, Ocampo, J. Electrochem. Soc. 103, 452, 682 (1956); Huebner, US 3025294 (1962 to Ciba). Pharmacology: P. B. S. Clarke et al., Br. J. Pharmacol. 111, 397 (1994). Use in studies of neuronal nicotinic acetylcholine receptors: A. S. Woods et al., J. Proteome Res. 2, 207 (2003).
Properties: Non-hygroscopic crystals contg ethanol of crystallization, mp 258-265° (dec). Sol in water, methanol, ethanol. pH of aq solns 4.7 to 6.2. Forms yellow, chloroform-soluble complex with bromcresol green, absorption max 420 nm.
Melting point: mp 258-265° (dec)
Absorption maximum: absorption max 420 nm
Use: Biochemical probe in nicotinic receptor studies.