Home > Name List By other > (2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid

CAS No 65002-17-7 , (2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid

  • Name: (2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid
  • Synonyms: Thiobutarit;Tiobutarit; Rimatil; DSSTox_CID_28513; CHEMBL80830; De-019;(2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid; N-(2-MERCAPTO-2-METHYL-1-OXOPROPYL)-; L-CYSTEINE; 65002-17-7;
  • CAS Registry Number:
  • Density: 1.289 g/cm3
  • Refractive index: 1.552
  • Safety Statements: Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx. An anti-rheumatic agent. See also MERCAPTANS.
  • Molecular Weight: 223.31302
  • InchiKey: VUAFHZCUKUDDBC-BYPYZUCNSA-N
  • InChI: InChI=1S/C7H13NO3S2/c1-7(2,13)6(11)8-4(3-12)5(9)10/h4,12-13H,3H2,1-2H3,
    (H,8,11)(H,9,10)/t4-/m0/s1
  • Molecular Formula: C7H13NO3S2
  • Molecular Structure:CAS No:65002-17-7 (2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid
Search by region :

Select to

65002-17-7 bucillamine

  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturers]
  • Tel: +86-(21)-64965859,64968085
  • Fax: +86-(21)-64968087
  • Address: Room 128, Building B, No. 8, Lane 1305, Huajing Road, Xuhui Area, Shanghai 200231, null,ShanghaiChina
Contact Supplier

65002-17-7 BUCILLAMINE

  • China FAITH EAGLE (LABORATORY) LTD. [Manufacturers]
  • Tel: (+86-755) 82851290
  • Fax: +86-755-83164680 83662918
  • Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China Shenzhen,GuangdongChina
Contact Supplier

65002-17-7 bucillamine

  • China Inter-Chemical Ltd. [Manufacturers]
  • Tel: +86-(755)-82187211, 82192202
  • Fax: +86-(755)-82187212
  • Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005, Shenzhen,GuangdongChina
Contact Supplier

65002-17-7 bucillamine

  • China Bo Jia Science and Technology (Wuhan) Co., Ltd. [Manufacturers]
  • Tel: 02787526690-8155
  • Fax: 86-027-87526527
  • Address: Wuhan City, Hubei Province Luo Yu Road, Hongshan No. 424 Technology Innovation Center, 14 Floor, Block A wuhan,hubeiChina
Contact Supplier

65002-17-7 bucillamine

  • China SOGA ENTERPRISES ASIA GROUP [Manufacturers]
  • Tel: +86-633-8332928
  • Fax: +86-633-8352255
  • Address: No.1,Huanghai Yilu.Rizhao,Shandong null,ShandongChina
Contact Supplier

65002-17-7 BUCILLAMINE

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
Contact Supplier

65002-17-7 BUCILLAMINE

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 null,nullCanada
Contact Supplier

65002-17-7 bucillamine

  • China NANTONG CHEM-TECH.(GROUP) CO.,LTD [Manufacturers]
  • Tel: 0086-513-85081108 85335860
  • Fax: 0086-513-85085921
  • Address: 7/F Beihao BLDG, No. 91,Zhongxiu Middle Road, Nantong,China Nantong,jiangsuChina
Contact Supplier

65002-17-7 bucillamine

Contact Supplier

65002-17-7 Bucillamine

  • Bucillamine, > 99% JP
  • China A SUN (Shanghai) Chemical Ind. Co., Ltd. [Manufacturer]
  • Tel: 86-21-54420995
  • Fax: 86-21-54420995
  • Address: Shenbei Road,555 Nong,43-502 Minhang District, Shanghai, China201108 ShanghaiCHINA Shanghai,nullChina
Contact Supplier

Select to

References of (2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid
Title: Bucillamine
CAS Registry Number: 65002-17-7
CAS Name: N-(2-Mercapto-2-methyl-1-oxopropyl)-L-cysteine
Synonyms: N-(2-mercapto-2-methylpropanoyl)-L-cysteine; N-(2-mercaptoisobutyryl)-L-cysteine; tiobutarit; thiobutarit
Manufacturers' Codes: DE-019; SA-96
Trademarks: Rimatil (Santen)
Molecular Formula: C7H13NO3S2
Molecular Weight: 223.31
Percent Composition: C 37.65%, H 5.87%, N 6.27%, O 21.49%, S 28.72%
Literature References: Disease modifying antirheumatic drug (DMARD) which modulates the immune response; structurally related to tiopronin, q.v. Prepn: T. Fujita et al., DE 2709820; eidem, US 4305958 (1977, 1981 both to Santen); M. Oya et al., Chem. Pharm. Bull. 29, 940 (1981). GC-MS determn in blood: K. Matsuura et al., J. Mass Spectrom. Soc. Jpn. 46, 25 (1998). Clinical immunopharmacology: H. Matsuno et al., Drugs Exp. Clin. Res. 19, 205 (1993). Clinical trials in rheumatoid arthritis: M. Yasuda et al., Clin. Rheumatol. 13, 446 (1994); H. A. Kim, Y. W. Song, Rheumatol. Int. 17, 5 (1997).
Properties: Crystals from ethyl acetate, mp 139-140°. [a]D25 +32.3° (c = 1.0 in ethanol). LD50 in mice (mg/kg): 2285 i.p.; 989.6 i.v. (Fujita, 1981).
Melting point: mp 139-140°
Optical Rotation: [a]D25 +32.3° (c = 1.0 in ethanol)
Toxicity data: LD50 in mice (mg/kg): 2285 i.p.; 989.6 i.v. (Fujita, 1981)
Therap-Cat: Antirheumatic.
Keywords: Antiarthritic/Antirheumatic; Immunomodulator.