Title: Ethyl Methanesulfonate
CAS Registry Number: 62-50-0
CAS Name: Methanesulfonic acid ethyl ester
Synonyms: ethyl methanesulfonic acid; ethyl mesylate; EMS
Manufacturers' Codes: NSC-26805
Molecular Formula: C3H8O3S
Molecular Weight: 124.16
Percent Composition: C 29.02%, H 6.49%, O 38.66%, S 25.83%
Line Formula: CH3SO2OCH2CH3
Literature References: Prepn: O. C. Billeter,
Ber. 38, 2015 (1905). Mutagenicity studies: T. Alderson,
Nature 207, 164 (1965); J. B. Jenkins,
Mutat. Res. 4, 90 (1967); A. P. Schalet,
ibid. 49, 313 (1978). Review of carcinogenicity studies:
IARC Monographs 7, 245-252 (1974). Review of comparative mutagenicity of EMS and methyl methanesulfonate,
q.v.: S. Kondo,
Environ. Sci. Res. 24, 743-785 (1981).
Properties: Liquid, bp761 213-213.5°; bp10 85-86°. d422 1.1452.
Boiling point: bp761 213-213.5°; bp10 85-86°
Density: d422 1.1452
CAUTION: This substance is reasonably anticipated to be a human carcinogen:
Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-124.
Use: Exptlly as mutagen, teratogen and brain carcinogen.