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CAS No 62-44-2 , N-(4-ethoxyphenyl)acetamide

  • Name: N-(4-ethoxyphenyl)acetamide
  • Synonyms: N-(4-ethoxyphenyl)acetamide; Contradouleur; Acetophenetidine; p-Acetophenetidide; N-(4-Ethoxyphenyl)acetamide; Acetophenetin; Acetphenetidin;Acetophenetidin;
  • CAS Registry Number:
  • Melting Point: 133-138 ºC
  • Boiling Point: 132 °C / 4mmHg
  • Density: 1.099 g/cm3
  • Refractive index: 1.505 (20 C)
  • Water Solubility: 0.076 G/100 ML
  • Safety Statements: R22;R45
  • Hazard Symbols: T: Toxic;
  • EINECS: 200-533-0
  • Molecular Weight: 179.21572
  • InchiKey: CPJSUEIXXCENMM-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,
    11,12)
  • Risk Statements: S45;S53
  • Molecular Formula: C10H13NO2
  • Molecular Structure:CAS No:62-44-2 N-(4-ethoxyphenyl)acetamide

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62-44-2 Phenacetin

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62-44-2 phenacetin

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62-44-2 Phenacetin

  • Chinese name: phenacetin CAS No: 62-44-2 Molecular formula: C10H13NO2 Molecular weight: 179.22 EINECS number: 200-533-0 Melting point 133-136 °C (lit.) Boiling point 132 °C / 4mmHg Storage conditions 2-8 ° C Use Paracetamol is used as a raw material ...
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62-44-2 Phenacetin

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62-44-2 Phenacetin

  • The painkiller phenacetin was the world's first synthetic pharmaceutical drug. It was developed by an American chemist and began distribution in 1887. Phenacetin was often accompanied by aspirin and caffeine in what were called APC pills, which were ...
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62-44-2 Phenacetin

  • The painkiller phenacetin was the world's first synthetic pharmaceutical drug. It was developed by an American chemist and began distribution in 1887. Phenacetin was often accompanied by aspirin and caffeine in what were called APC pills, which were ...
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62-44-2 Phenacetin Alias: 4-acetophenetidine;4-ETHOXYACETANILIDE;ACETOPHENETIDIN CAS: 62-44-2

  • Phenacetin Alias: 4-acetophenetidine;4-ETHOXYACETANILIDE;ACETOPHENETIDIN CAS: 62-44-2 EINECS: 200-533-0 M.F.: C10H13NO2 M.W.: 179.22 Purity: 99% Appearance:white crystalline powder Application:pharmaceutical intermediates M.S.: M.P.: 133-136 °C Compe...
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References of N-(4-ethoxyphenyl)acetamide
Title: Phenacetin
CAS Registry Number: 62-44-2
CAS Name: N-(4-Ethoxyphenyl)acetamide
Synonyms: p-acetophenetidide; p-ethoxyacetanilide; acetophenetidin; para-acetphenetidin; acet-p-phenetidin; p-acetophenetide
Molecular Formula: C10H13NO2
Molecular Weight: 179.22
Percent Composition: C 67.02%, H 7.31%, N 7.82%, O 17.85%
Literature References: Prepn: Beilstein vol. XIII, 461. Improved process: Eaker, Campbell, US 2887513 (1959 to Monsanto). Monograph: P. K. Smith, Acetophenetidin (Interscience, New York, 1958) 180 pp. Toxicity: Boyd, Toxicol. Appl. Pharmacol. 1, 240 (1959). Review of toxicity and metabolism studies: L. Fishbein, IARC Sci. Publ. 40, 287-310 (1981). Epidemiologic study of renal morbidity and mortality: U. C. Dubach et al., N. Engl. J. Med. 308, 357 (1983). Evaluation of renal effects: D. P. Sandler et al., ibid. 320, 1238 (1989).
Properties: Slightly bitter, cryst scales or powder. mp 134-135°. One gram dissolves in 1310 ml cold water, 82 ml boiling water; 15 ml cold alcohol, 2.8 ml boiling alcohol; 14 ml chloroform, 90 ml ether; sol in glycerol. Gives a pasty mass with phenol, chloral hydrate or pyrocatechol, strong acids or alkalies, salicylic acid, oxidizers, iodine, spirit nitrous ether. LD50 orally in rats: 1.65 g/kg (Boyd).
Melting point: mp 134-135°
Toxicity data: LD50 orally in rats: 1.65 g/kg (Boyd)
NOTE: Component of APC tablets, analgesic mixture also containing aspirin and caffeine.
CAUTION: Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing phenacetin are listed as known human carcinogens: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-212.
Therap-Cat: Analgesic, antipyretic.
Therap-Cat-Vet: Analgesic, antipyretic.
Keywords: Analgesic (Non-Narcotic); Antipyretic.