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CAS No 616-91-1 , (2R)-2-acetamido-3-sulfanylpropanoic acid

  • Name: (2R)-2-acetamido-3-sulfanylpropanoic acid
  • Synonyms: (2R)-2-acetamido-3-sulfanylpropanoic acid; Mucosil;N-Acetyl-L-cysteine; Parvolex; Broncholysin; Fluimucil; N-Acetylcysteine; Acetadote; mercapturic acid; Mucomyst; acetylcysteine;
  • CAS Registry Number:
  • Melting Point: 109-111 ºC
  • Density: 1.294 g/cm3
  • Refractive index: 24 ° (C=JPC Method)
  • Alpha: -35.1 ºC (C=2,H2O)
  • Safety Statements: S24/25; S22
  • HS Code: 29309016
  • EINECS: 210-498-3
  • Molecular Weight: 163.19486
  • InchiKey: PWKSKIMOESPYIA-BYPYZUCNSA-N
  • InChI: InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,
    9)/t4-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C5H9NO3S
  • Molecular Structure:CAS No:616-91-1 (2R)-2-acetamido-3-sulfanylpropanoic acid

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616-91-1 N-ACETYL L-CYSTEIN

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616-91-1 N-Acetyl-L-cysteine

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616-91-1 N-Acetyl-L-Cysteine

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616-91-1 Argireline Acetyl hexapeptide-3

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616-91-1 N-ACETYL-L-CYSTEIN

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616-91-1 ACETYLCYSTEINE (N-ACETYL-L-CYSTEINE)

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References of (2R)-2-acetamido-3-sulfanylpropanoic acid
Title: Acetylcysteine
CAS Registry Number: 616-91-1
CAS Name: N-Acetyl-L-cysteine
Synonyms: L-a-acetamido-b-mercaptopropionic acid; N-acetyl-3-mercaptoalanine
Trademarks: Acetadote (Cumberland); Brunac (Bruschettini); Fabrol (Zyma); Fluimucil (Zambon); Fluprowit (Thiemann); Mucocedyl (3M); Mucolator (Abbott); Mucomyst (BMS); Muco Sanigen (Thiemann); Mucosil (Dey); Mucret (Pharma-Stern); Neo-Fluimucil (Zambon); Parvolex (Evans); Tixair (Madaus)
Molecular Formula: C5H9NO3S
Molecular Weight: 163.19
Percent Composition: C 36.80%, H 5.56%, N 8.58%, O 29.41%, S 19.65%
Literature References: Thiol-containing antioxidant. Prepn: Smith, Gorin, J. Org. Chem. 26, 820 (1961). Prepn and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson). Effect in corneal healing: F. Menna et al., Bull. Mem. Soc. Fr. Opthalmol. 94, 425 (1982); G. Petroutsos et al., Ophthalmic Res. 14, 241 (1982). Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Clinical trial in acetaminophen overdose: M. J. Smilkstein et al., N. Engl. J. Med. 319, 1557 (1988); as renal protectant with radiocontrast agents: M. Tepel et al., ibid. 343, 180 (2000). Review: G. R. McKinney, G. M. Sisson, in Pharmacological and Biochemical Properties of Drug Substances vol. 2, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1979) pp 479-488. Review of use in clinical toxicology: R. J. Flanagan, T. J. Meredith, Am. J. Med. 91, Suppl. 3C, 131S-139S (1991).
Properties: Crystals from water, mp 109-110°. LD50 orally in rats: 5050 mg/kg (Goldenthal).
Melting point: mp 109-110°
Toxicity data: LD50 orally in rats: 5050 mg/kg (Goldenthal)
Therap-Cat: Mucolytic; corneal vulnerary; antidote (acetaminophen poisoning).
Therap-Cat-Vet: Expectorant.
Keywords: Antidote (Acetaminophen Poisoning); Mucolytic; Vulnerary.