Home > Name List By 5 > 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide

CAS No 61422-45-5 , 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide

  • Name: 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
  • Synonyms: 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide; 61422-45-5;carmofur; Yamaful; Mifurol; 1-(n-hexylcarbamoyl)-5-fluorouracil; Carmofurum [INN-Latin]; 1-Hexylcarbamoyl-5-fluorouracil; HCFU;
  • CAS Registry Number:
  • Melting Point: 110-111ºC
  • Density: 1.26 g/cm3
  • Refractive index: 1.525
  • Hazard Symbols: Xi: Irritant;
  • Molecular Weight: 257.261443
  • InchiKey: AOCCBINRVIKJHY-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/
    h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
  • Molecular Formula: C11H16FN3O3
  • Molecular Structure:CAS No:61422-45-5 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide

Related products

Search by region :

Select to

61422-45-5 Carmofur

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
Contact Supplier

61422-45-5 Carmofur

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

61422-45-5 Carmofur

  • Carmofur 61422-45-5 B120113
  • China bepharm ltd. null
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China null,nullChina
Contact Supplier

61422-45-5 Carmofur

Contact Supplier

61422-45-5 1-(n-Hexylcarbamoyl)-5-fluorouracil

  • 1-(n-Hexylcarbamoyl)-5-fluorouracil, 98% min.
  • United States SynQuest Laboratories, Inc. [Manufacturer]
  • Tel: 1-386-462-0788
  • Fax: 1-386-462-7097
  • Address: P.O.BOX309ALACHUA,FL32616-0309 ALACHUAUNITED STATES ALACHUA,nullUnited States
Contact Supplier

61422-45-5 Carmofur

Contact Supplier

61422-45-5 Carmofur

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
Contact Supplier

61422-45-5 Carmofur

Contact Supplier

61422-45-5 Carmofur

  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
Contact Supplier

61422-45-5 Carmofur, 99%

  • Carmofur, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
Contact Supplier

Select to

2/6
Previous 1 2 3 4 5 6 Next
References of 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
Title: Carmofur
CAS Registry Number: 61422-45-5
CAS Name: 5-Fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinecarboxamide
Synonyms: 1-(n-hexylcarbamoyl)-5-fluorouracil; HCFU
Trademarks: Mifurol (Mitsui); Yamaful (Yamanouchi)
Molecular Formula: C11H16FN3O3
Molecular Weight: 257.26
Percent Composition: C 51.36%, H 6.27%, F 7.38%, N 16.33%, O 18.66%
Literature References: Orally active cytostatic deriv of fluorouracil, q.v. Prepn: S. Ozaki et al., JP Kokai 77 78886, C.A. 87, 152265 (1977); eidem, US 4071519 (1977, 1978 both to Mitsui); eidem, Bull. Chem. Soc. Jpn. 50, 2406 (1977). Anti-tumor activity: A. Hoshi et al., Chem. Pharm. Bull. 26, 161 (1978). Determn in body fluids: S. Watanabe et al., Chemotherapy (Tokyo) 27, 778 (1979); O. Nakajima et al., J. Chromatogr. 225, 91 (1981). General pharmacology: Z. Henmi et al., Oyo Yakuri 19, 369 (1980), C.A. 93, 125639s (1980). Pharmacokinetics: M. Iigo et al., Cancer Chemother. Pharmacol. 4, 189 (1980). Metabolism: eidem, Xenobiotica 10, 847 (1980); T. Kobari et al., ibid. 11, 57 (1981). Phase I clinical study: Y. Koyama, Y. Koyama, Cancer Treat. Rep. 64, 861 (1980). Mutagenicity study: Y. Seino et al., Cancer Res. 38, 2148 (1978). Review: T. Taguchi, Recent Results Cancer Res. 70, 125-132 (1980).
Properties: White cryst from ethanol, mp 110-111°. uv max (chloroform): 258 nm (e 1.16 ′ 104) (S. Ozaki et al., Bull. Chem. Soc. Japan). Also reported as mp 283° (dec) (US 4071519).
Melting point: mp 110-111°; mp 283° (dec) (US 4071519)
Absorption maximum: uv max (chloroform): 258 nm (e 1.16 ′ 104) (S. Ozaki et al., Bull. Chem. Soc. Japan)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs.