Home > Name List By 2 > 2-(2,3-dimethylanilino)benzoic acid Germany

CAS No 61-68-7 , 2-(2,3-dimethylanilino)benzoic acid Search by region : Germany

  • Name: 2-(2,3-dimethylanilino)benzoic acid
  • Synonyms: Mefacit; Bonabol;2-(2,3-dimethylanilino)benzoic acid; Lysalgo; Ponstan;Ponstel; Coslan; Ponalar; Parkemed; Vialidon;
  • CAS Registry Number:
  • Melting Point: 230 °C
  • Density: 1.203 g/cm3
  • Refractive index: 1.639
  • Water Solubility: insoluble
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-513-1
  • Molecular Weight: 241.2851
  • InchiKey: HYYBABOKPJLUIN-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/
    h3-9,16H,1-2H3,(H,17,18)
  • Risk Statements: S22:Donotinhaledust.;S36/37:Wearsuitableprotectiveclothingandgloves.;
  • Molecular Formula: C15H15NO2
  • Molecular Structure:CAS No:61-68-7 2-(2,3-dimethylanilino)benzoic acid

Related products

Select to

61-68-7 MEFENAMIC ACID

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany null,nullGermany
Contact Supplier

61-68-7 MEFENAMIC ACID

  • Germany CEDA Chemicals GmbH [Manufacturer]
  • Tel: + 49 - 25 94 - 78 31 40 - 0
  • Fax: + 49 - 25 94 - 78 31 40 - 22
  • Address: CEDA Chemicals GmbH
    Fehrbelliner Platz 1
    D-48249 D?lmen
    Germany null,nullGermany
Contact Supplier

Select to

1/1
References of 2-(2,3-dimethylanilino)benzoic acid
Title: Mefenamic Acid
CAS Registry Number: 61-68-7
CAS Name: 2-[(2,3-Dimethylphenyl)amino]benzoic acid
Synonyms: N-(2,3-xylyl)anthranilic acid
Manufacturers' Codes: CI-473; INF-3355
Trademarks: Lysalgo (SIT); Mefenacid (Streuli); Parkemed (Parke-Davis); Ponalar (Parke-Davis); Ponstan (Pfizer); Ponstel (Warner-Lambert); Ponstyl (Parke-Davis); Pontal (Parke-Davis)
Molecular Formula: C15H15NO2
Molecular Weight: 241.29
Percent Composition: C 74.67%, H 6.27%, N 5.80%, O 13.26%
Literature References: Prepn: BE 605302; R. A. Scherrer, US 3138636 (1961, 1964 both to Parke-Davis). Pharmacology: C. V. Winder et al., J. Pharmacol. Exp. Ther. 138, 405 (1962); C. V. Winder et al., Arthritis Rheum. 12, 472 (1969); and toxicology: Mokhort, Korkhova, Farmakol. Toksikol. (Kiev) 1968, 85, C.A. 71, 29080c (1969); U. Jahn, R. W. Adrian, Arzneim.-Forsch. 19, 36 (1969). Crystal structure: J. F. McConnell, F. Z. Company, Cryst. Struct. Commun. 5, 861 (1976). Clinical trial in primary dysmenorrhea: P. W. Budoff, J. Am. Med. Assoc. 241, 2713 (1979). HPLC determn in human plasma: I. Niopas, K. Mamzoridi, J. Chromatogr. B 656, 447 (1994).
Properties: Crystals, mp 230-231° (effervescence). pKa 4.2. uv max (0.lN NaOH): 285, 340 nm. Soly in H2O, pH 7.1 (g/100 ml): 0.0041 (25°); 0.008 (37°). Soluble in solns of alkali hydroxides; sparingly sol in ether, chloroform; slightly sol in ethanol. LD50 orally in mice, rats: 630, 790 mg/kg (Jahn, Adrian).
Melting point: mp 230-231° (effervescence)
pKa: pKa 4.2
Absorption maximum: uv max (0.lN NaOH): 285, 340 nm
Toxicity data: LD50 orally in mice, rats: 630, 790 mg/kg (Jahn, Adrian)
 
Derivative Type: Sodium salt
Molecular Formula: C15H14NNaO2
Molecular Weight: 263.27
Percent Composition: C 68.43%, H 5.36%, N 5.32%, Na 8.73%, O 12.15%
Properties: White powder. Soly in H2O: >5 g/100 ml. LD50 in mice (mg/kg): 600 orally; 150 i.p. (Mokhort, Korkhova).
Toxicity data: LD50 in mice (mg/kg): 600 orally; 150 i.p. (Mokhort, Korkhova)
 
Therap-Cat: Anti-inflammatory; analgesic.
Keywords: Anti-inflammatory (Nonsteroidal); Aminoarylcarboxylic Acid Derivatives.