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CAS No 6064-83-1 , 2-phosphonooxybenzoic acid

  • Name: 2-phosphonooxybenzoic acid
  • Synonyms: 2-(Phosphonooxy)benzoic acid;2-phosphonooxybenzoic acid; Salicyl phosphate; Disdolen; 6064-83-1; 2-Carboxyphenyl phosphate; o-Carboxyphenyl phosphate;
  • CAS Registry Number:
  • Flash Point: 245.5°C
  • Boiling Point: 482.3°C at 760 mmHg
  • Safety Statements: R22:Harmfulifswallowed.;
  • Hazard Symbols: Xn
  • Flash Point: 245.5°C
  • EINECS: 227-993-5
  • Molecular Weight: 218.100642
  • InchiKey: FFKUDWZICMJVPA-UHFFFAOYSA-N
  • InChI: InChI=1S/C7H7O6P/c8-7(9)5-3-1-2-4-6(5)13-14(10,11)12/h1-4H,(H,8,9)(H2,
    10,11,12)
  • Risk Statements: S22:Donotinhaledust.;S36/37:Wearsuitableprotectiveclothingandgloves.;
  • Molecular Formula: C7H7O6P
  • Molecular Structure:CAS No:6064-83-1 2-phosphonooxybenzoic acid

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6064-83-1 2-CARBOXYPHENYL PHOSPHATE

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6064-83-1 FOSFOSAL

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6064-83-1 2-CARBOXYPHENYL PHOSPHATE

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6064-83-1 O-CARBOXYPHENYL PHOSPHATE

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References of 2-phosphonooxybenzoic acid
Title: Fosfosal
CAS Registry Number: 6064-83-1
CAS Name: 2-(Phosphonooxy)benzoic acid
Synonyms: salicylic acid dihydrogen phosphate; o-carboxyphenyl phosphate; salicyl phosphate
Manufacturers' Codes: UR-1521
Trademarks: Disdolen (Uriach)
Molecular Formula: C7H7O6P
Molecular Weight: 218.10
Percent Composition: C 38.55%, H 3.24%, O 44.01%, P 14.20%
Literature References: Salicylic acid deriv. Prepn: A. C. Marin Moga, E. Francia Barra, DE 2641526 (1978 to Uriach), C.A. 88, 136317h (1978). Pharmacology and comparison with aspirin: J. Garcia Rafanell et al., Arzneim.-Forsch. 30, 1091 (1980). Toxicity studies: M. S. Sanchez et al., ibid. 1098. Pharmacokinetics: V. Rimbau et al., Arch. Farmacol. Toxicol. 7, 61 (1981). Double-blind trials in musculoskeletal/articular pain: C. Diaz et al., Clin. Ther. 4, 121 (1981); L. Madera Cat, J. Garcia Rafanell, Med. Clin. 76, 18 (1981).
Properties: White solid, mp 168-170°. Sol in water, ethanol, acetone. Insol in non-polar organic solvents. Hydrolyzes in aq soln. LD50 in male, female mice, male, female rats at pH 1.0, aq soln (mg/kg): 94, 105, 153, 257 i.v.; 352, 253, 338, 360 i.p.; 1455, 1539, 1104, 1213 orally; at pH 3.5 (mg/kg): 117, 118, 207, 215 i.v.; 1592, 1483, 1085, 1128 i.p.; 1702, 2007, 1685, 2225 orally (Sanchez).
Melting point: mp 168-170°
Toxicity data: LD50 in male, female mice, male, female rats at pH 1.0, aq soln (mg/kg): 94, 105, 153, 257 i.v.; 352, 253, 338, 360 i.p.; 1455, 1539, 1104, 1213 orally; at pH 3.5 (mg/kg): 117, 118, 207, 215 i.v.; 1592, 1483, 1085, 1128 i.p.; 1702, 2007, 1685, 2225 orally (Sanchez)
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).